عنوان

Benzodiazepines II :

(Number (ISBN

3642740316

(Number (ISBN

9783642740312

Number

b573238

Title Proper

Benzodiazepines II :

General Material Designation

[Book]

Other Title Information

a Handbook. Basic Data, Analytical Methods, Pharmacokinetics, and Comprehensive Literature

First Statement of Responsibility

by Harald Schütz.

Place of Publication, Distribution, etc.

Berlin, Heidelberg

Name of Publisher, Distributor, etc.

Springer Berlin Heidelberg

Date of Publication, Distribution, etc.

1989

Specific Material Designation and Extent of Item

(xiii, 623 pages 183 illustrations)

Text of Note

Index of Treated Substances.- List of Synonyma.- Biotransformation.- Formation of the Hydrolysis Derivatives.- TLC-Data.- Thin-Layer Chromatography - The Concept of the Corrected Rf-Value (Rfc-Value).- Screening of the Benzodiazepines via Rfc-Values.- Screening of the Benzodiazepines via Aminobenzophenones and Bratton-Marshall Detection.- GLC-Data and UV-Spectra.- Gas Chromatography - The Concept of the Retention Index.- List of UV-Maxima.- UV-Spectra (Ultraviolet-Spectra).- List of Important m/z-Values.- Infrared- and Mass-Spectra.- Immunological Methods.- Presentation of Analytical Methods.- Methods for the Determination of New Benzodiazepines.- alprazolam.- brotizolam.- clotiazepam.- delorazepam, chlordesmethyldiazepam.- estazolam.- ethyl loflazepate.- flumazenil, Ro 15-1788.- halazepam.- metaclazepam.- midazolam.- pinazepam.- quazepam.- temazepam.- tetrazepam.- triazolam.- Additional Methods for the Determination of Benzodiazepines Already Described in Vol. I.- Simultaneous Methods.- Mono Methods.- bromazepam.- clobazam.- clonazepam.- diazepam.- flunitrazepam.- flurazepam.- lorazepam.- nitrazepam.- List of Therapeutic and Toxic Concentrations.- Blood-, Serum- and Plasma-Levels and Other Pharmacokinetic Data from Literature.- alprazolam.- brotizolam.- clotiazepam.- delorazepam, chlordesmethyldiazepam.- estazolam.- ethyl loflazepate.- flumazenil, Ro 15-1788.- halazepam.- loprazolam.- metaclazepam.- midazolam.- oxazolam.- pinazepam.- quazepam.- temazepam.- tetrazepam.- triazolam.- Survey of Benzodiazepine Literature.- 1 Absorption Studies.- 2 Analytical Studies.- 3 Antagonist Studies.- 4 Anesthesia Studies.- 5 Behavioral Studies.- 6 Biotransformation/Metabolism.- 7 Casuistics.- 8 Feto-Maternal-Studies.- 9 GABA-Studies.- 10 Galenic Studies.- 11 Gas-Chromatography.- 12 High-Pressure-Liquid-Chromatography.- 13 Hydrolysis Studies.- 14 Immunoassays (RIA, EMIT, TDx and Others).- 15 Interactions.- 16 Mass-Spectrometry.- 17 NMR-Studies.- 18 Pharmacokinetics (Levels).- 19 Pharmacology and Clinical Studies.- 20 Photometry (UV-, IR-, VIS-, Fluorometry).- 21 Polarography.- 22 Protein Binding.- 23 Radioactive-Labelled Compounds.- 24 Radioreceptor Assays.- 25 Receptor Studies.- 26 Review Articles.- 27 Screening Methods.- 28 Side-, Adverse-, Residual-Effects.- 29 Sleep Studies.- 30 Synthesis of Benzodiazepines.- 31 TLC-Studies.- 32 Toxicity.- 33 Miscellaneous.- References.

Text of Note

This completely new volume is a companion to Benzodiazepines by the same editor, which has established itself as a standard work since it appeared in 1982. Benzodiazepines II contains a complete update of information, with new substances as well as new methods of analysis and pharmacokinetics. A comprehensive list of more than 7500 references is a special feature which makes the volume a practical guide for the non-analyst as well. From the reviews of Benzodiazepines: "This publication is valuable as an up-to-date reference work on benzodiazepine literature and on the relevant chemical, analytical and pharmacological data contained therein. It merits a place in the laboratories and libraries of those institutions where analytical, pharmacological, toxicological and clinical investigations are taking place." Analyst#1.

Analytical biochemistry.

Medicine.

Toxicology.

Class number

Book number

by Harald Schütz.

Harald Schütz

Electronic name

[Book]

Y