Target organ toxicology in Caenorhabditis elegans /
نام عام مواد
[Book]
نام نخستين پديدآور
Dayong Wang.
وضعیت نشر و پخش و غیره
محل نشرو پخش و غیره
Singapore :
نام ناشر، پخش کننده و غيره
Springer,
تاریخ نشرو بخش و غیره
[2019]
مشخصات ظاهری
نام خاص و کميت اثر
1 online resource
یادداشتهای مربوط به کتابنامه ، واژه نامه و نمایه های داخل اثر
متن يادداشت
Includes bibliographical references.
یادداشتهای مربوط به مندرجات
متن يادداشت
Intro; Preface; Contents; Chapter 1: Protective Responses of Different Organs to Environmental Toxicants or Stresses; 1.1 Introduction; 1.2 Protective Responses to Environmental Toxicants or Stresses in the Intestine; 1.2.1 Superoxide Dismutase (SOD) Proteins; 1.2.2 MTL-1 and MTL-2; 1.2.3 Heat Shock Proteins (HSPs); 1.2.4 PMK-1, SKN-1/Nrf, and GST-4; 1.2.5 Transcriptional Factor DAF-16; 1.2.6 Antimicrobial Proteins; 1.2.7 Mitochondrial Unfolded Protein Response (UPR); 1.2.8 Endoplasmic Reticulum (ER) UPR; 1.2.9 Autophagy
متن يادداشت
1.3 Protective Responses to Environmental Toxicants or Stresses in Epidermis1.3.1 Antimicrobial Proteins; 1.3.2 Autophagy; 1.4 Protective Responses to Environmental Toxicants or Stresses in Neurons; 1.4.1 SKN-1/Nrf; 1.4.2 JNK Signaling; 1.4.3 ERK Signaling; 1.4.4 Antimicrobial Proteins; 1.4.5 Autophagy; 1.5 Protective Responses to Environmental Toxicants or Stresses in Muscle; 1.6 Perspectives; References; Chapter 2: Avoidance Behavior of Nematodes to Environmental Toxicants or Stresses; 2.1 Introduction
متن يادداشت
2.2 Neurons Involved in the Regulation of Avoidance Behavior to Environmental Toxicants or Stress2.2.1 ASH Sensory Neurons; 2.2.1.1 Involvement of ASH Sensory Neurons in Response to Environmental Toxicants or Stresses; 2.2.1.2 Molecular Basis for ASH Sensory Neurons in Response to Environmental Toxicants or Stresses; 2.2.1.2.1 G Proteins; 2.2.1.2.2 Seven-Transmembrane Protein DCAR-1; 2.2.1.2.3 Neurotransmitter Signals; 2.2.2 ADL Sensory Neurons; 2.2.2.1 Involvement of ADL Sensory Neurons in Response to Environmental Toxicants or Stresses
متن يادداشت
2.2.2.2 Molecular Basis for ADL Sensory Neurons in Response to Environmental Toxicants or Stresses2.2.3 ASK Sensory Neurons; 2.2.4 ASJ Sensory Neurons; 2.2.4.1 Involvement of ASJ Sensory Neurons in Response to Environmental Toxicants or Stresses; 2.2.4.2 Molecular Basis for ASJ Sensory Neurons in Response to Environmental Toxicants or Stresses; 2.2.5 ADF Sensory Neurons; 2.2.6 ASI Sensory Neurons; 2.2.7 AWB Sensory Neurons; 2.2.8 AWC Sensory Neurons; 2.2.9 BAG Sensory Neurons; 2.2.9.1 Involvement of BAG Sensory Neurons in Response to Environmental Toxicants or Stresses
متن يادداشت
2.2.9.2 Molecular Basis for BAG Sensory Neurons in Response to Environmental Toxicants or Stresses2.2.10 OLL Sensory Neurons; 2.2.11 Interneurons; 2.3 Neuronal Circuit for the Avoidance Behavior to Environmental Toxicants or Stresses and the Underlying Molecular Basis; 2.3.1 ASI-ADF-ASH and ASH-RIC-ASI Neuronal Circuits; 2.3.1.1 ASI-ADF-ASH Neuronal Circuit; 2.3.1.2 ASH-RIC-ASI Neuronal Circuit; 2.3.1.3 Cross-Inhibitory Neural Circuitry Between ASHs and ASIs; 2.3.2 ADL-AIB Neuronal Circuit; 2.3.3 ASJ-RIM/RIC Neuronal Circuit; 2.3.4 AWB-AIZ/RMG Neuronal Circuit; 2.3.5 OLL-RMG Neuronal Circuit
بدون عنوان
0
بدون عنوان
8
بدون عنوان
8
بدون عنوان
8
بدون عنوان
8
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
This book introduces readers to intestinal and epidermal barriers, and to toxicity induction of environmental toxicants or stresses in the intestine, epidermis, neurons, muscle, and reproductive organs in Caenorhabditis elegans. In addition, it discusses the protective responses of various organs and nematodes' avoidance behaviour with regard to environmental toxicants or stresses. The intestinal, epidermal, neuronal, and germline signalling pathways required for the regulation of toxicity of environmental toxicants or stresses are also introduced and discussed. As a classic model animal with well-described genetic and developmental backgrounds, the nematode Caenorhabditis elegans has been successfully and widely used in both toxicity assessments and toxicological studies on various environmental toxicants and stresses. Once exposure to certain environmental toxicants has occurred, the toxicants can enter into the primary targeted organs (such as intestinal cells), and even be translocated into secondary targeted organs (such as reproductive organs and neurons). Based on related available data, this book provides a systematic understanding of target organ toxicology in C. elegans.
یادداشتهای مربوط به سفارشات
منبع سفارش / آدرس اشتراک
Springer Nature
شماره انبار
com.springer.onix.9789811360107
ویراست دیگر از اثر در قالب دیگر رسانه
عنوان
Target organ toxicology in Caenorhabditis elegans.
شماره استاندارد بين المللي کتاب و موسيقي
9789811360091
موضوع (اسم عام یاعبارت اسمی عام)
موضوع مستند نشده
Caenorhabditis elegans-- Toxicology.
موضوع مستند نشده
Target organs (Anatomy)
موضوع مستند نشده
SCIENCE-- Life Sciences-- Zoology-- General.
موضوع مستند نشده
Target organs (Anatomy)
مقوله موضوعی
موضوع مستند نشده
MKG
موضوع مستند نشده
MMG
موضوع مستند نشده
SCI-- 070000
رده بندی ديویی
شماره
595
.
182
ويراست
23
رده بندی کنگره
شماره رده
QL391
.
N4
نام شخص به منزله سر شناسه - (مسئولیت معنوی درجه اول )