عنوان

Molecular defects in cardiovascular disease /

شابک

1441971297

شابک

1441971300

شابک

9781441971296

شابک

9781441971302

شماره

b430525

عنوان اصلي

Molecular defects in cardiovascular disease /

نام عام مواد

[Book]

نام نخستين پديدآور

Naranjan S. Dhalla, Makoto Nagano, Bohuslav Ostadal, editors

نام خاص و کميت اثر

1 online resource (xviii, 382 pages) :

ساير جزييات

illustrations (some color)

متن يادداشت

Includes bibliographical references and index

متن يادداشت

Calcium Overloading-Induced Oxidative Stress-Mediated Cellular and Subcellular Remodeling -- Intracellular MMP-2: Role in Normal and Diseased Hearts -- Control of the Mesenchymal-Derived Cell Phenotype by Ski and Meox2: A Putative Mechanism for Postdevelopmental Phenoconversion -- Elevated Na+-H+ Exchanger Expression and Its Role in Myocardial Dise -- Impact of Perinatal Chronic Hypoxia on Cardiac Tolerance to Acute Ischemia -- Stem Cell, MicroRNA and Redox Cycling -- Cardiac Cell Therapy: Present and Future -- Macroscopic and Microscopic Aspects of Cardiac Dysfunction in Congestive Heart Failure -- Cardiac Dysfunction and Metabolism: Unravelling the Molecular Cross-Talk -- Metabolic Remodelling of the Hypertrophied Heart -- Mechanisms for the Regulation of Phospholipase C Gene Expression in Cardiac Hypertrophy -- Molecular Changes in Fatty Acid Oxidation in the Failing Heart -- Cardiolipin Metabolism in Experimental and Human Heart Failure -- Mechanisms Underlying Development of Cardiomyocyte Hypertrophy via Na-H Exchange Stimulation -- The Structural Basis of Cardiac Dysfunction in Human Heart Failure -- Hormonal Mechanisms of Cardiac Remodeling in Heart Failure -- Modulators of Remodeling After Myocardial Infarction -- Phosphodiesterase-5 Inhibitors in Protection Against Doxorubicin-Induced Cardiomyopathy -- Molecular Basis of Pulmonary Hypertension in Left Heart Failure -- Modulation of Gi Protein Expression in Hypertension: Molecular Mechanisms -- Vascular Dysfunction in Heart Disease -- Cellular and Molecular Mechanisms Associated with Salicylate Inhibition of Intimal Hyperplasia Following Balloon Catheter-Induced Vascular Injury -- Involvement of Growth Factor Receptor and Nonreceptor Protein Tyrosine Kinases in Endothelin-1 and Angiotensin II-Induced Signaling Pathways in the Cardiovascular System -- Sarco/Endoplasmic Reticulum Ca2+ Pump Damage by Oxidative Stress: Implications for Ca2+ Entry -- Obesity-Hypertension: Leptin as the Common Link to Cardiovascular and Renal Dysregulation -- Cardiorenal Protection in Diabetes Mellitus -- Molecular Mechanisms in the Pathogenesis of Diabetic Cardiomyopathy

بدون عنوان

0

متن يادداشت

Molecular Defects in Cardiovascular Disease¡provides an in-depth discussion of the molecular mechanisms underlying the genesis of cardiovascular defects and the implications this has on current and emerging targeted therapeutics.¡ Divided into three sections, this book covers the scientific foundations of our present understanding as well as the array of clinical manifestations and their treatment.¡ The first section covers Molecular Mechanisms of Heart Disease, with discussion of the development of cardiovascular dysfunction.¡ The remaining two sections provide a more clinical focus.¡ The second, Cardiac Hypertrophy and Heart Failure deals with metabolic derangements, Ca2+ handling, and subcellular remodeling. ¡It illustrates the wide variety of molecular defects which may serve as targets associated with the transition from cardiac hypertrophy to advanced heart failure.¡ The third section, Hypertension and Diabetes, provides molecular rationale for the pathogenesis of hypertension and diabetic cardiomyopathy, as well as highlighting the importance of hormones toward this end.¡ ¡ A necessary resource for clinicians and researchers, this book elucidates the experimental basis of the practice of cardiology.¡ It is the culmination of our advances in the understanding of cardiovascular molecular biology and a blueprint for the efficacious use of targeted therapies

منبع سفارش / آدرس اشتراک

Springer

شماره انبار

978-1-4419-7129-6

عنوان

Molecular defects in cardiovascular disease.

موضوع مستند نشده

Cardiovascular system-- Diseases-- Molecular aspects

موضوع مستند نشده

Cardiovascular Diseases-- pathology.

موضوع مستند نشده

Molecular Biology.

موضوع مستند نشده

Medical Biochemistry

موضوع مستند نشده

Medicine & Public Health

موضوع مستند نشده

MED010000

موضوع مستند نشده

MJD

شماره

ويراست

شماره رده

نشانه اثر

شماره رده

مستند نام اشخاص تاييد نشده

Dhalla, Naranjan S

مستند نام اشخاص تاييد نشده

Nagano, Makoto,1928-

مستند نام اشخاص تاييد نشده

Ošt̕ádal, Bohuslav

تاريخ عمليات

20170726082053.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y