عنوان

Redirection of Th1 and Th2 Responses

3662097095

9783662097090

b580314

Redirection of Th1 and Th2 Responses

[Book]

edited by Robert L. Coffman, Sergio Romagnani.

Berlin, Heidelberg

Springer Berlin Heidelberg

1999

(ix, 150 pages)

Current topics in microbiology and immunology, 238.

The Stability and Reversibility of Th1 and Th2 Populations --; T Helper Differentiation Proceeds Through Stat1-Dependent, Stat4-Dependent and Stat4-Independent Phases --; Redirecting Th2 Responses in Allergy --; Interleukin-12: Basic Principles and Clinical Applications --; Redirecting Th1 and Th2 Responses in Autoimmune Disease --; Manipulation of the Th Responses of Oral Tolerance.

The two major subsets of CD4+ helper T cells, designated Th1 and Th2, have quite different patterns of cytokine production and, as a consequence, have very different roles in immune responses. The articles in this volume review both basic and clinical studies of T cell heterogeneity, including: - The mechanisms by which Th1 and Th2 cells develop and maintain their differences in cytokine production - The different roles of Th1 and Th2 cells in allergy, autoimmunity and infectious diseases - The prospects and strategies for therapeutic manipulation of Th1 and Th2 cells - The control of Th1 and Th2 responses by regulatory T cell subsets. The volume will give the reader a current view of the development and function of Th1 and Th2 cells and the attempts to treat immunological diseases with therapies directed towards altering the Th1/Th2 balance.

Immunology.

Medicine.

Oncology.

edited by Robert L. Coffman, Sergio Romagnani.

Robert L Coffman

S Romagnani

[Book]

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