عنوان

Redirection of Th1 and Th2 Responses

(Number (ISBN

3662097095

(Number (ISBN

9783662097090

Number

b580314

Title Proper

Redirection of Th1 and Th2 Responses

General Material Designation

[Book]

First Statement of Responsibility

edited by Robert L. Coffman, Sergio Romagnani.

Place of Publication, Distribution, etc.

Berlin, Heidelberg

Name of Publisher, Distributor, etc.

Springer Berlin Heidelberg

Date of Publication, Distribution, etc.

1999

Specific Material Designation and Extent of Item

(ix, 150 pages)

Series Title

Current topics in microbiology and immunology, 238.

Text of Note

The Stability and Reversibility of Th1 and Th2 Populations --; T Helper Differentiation Proceeds Through Stat1-Dependent, Stat4-Dependent and Stat4-Independent Phases --; Redirecting Th2 Responses in Allergy --; Interleukin-12: Basic Principles and Clinical Applications --; Redirecting Th1 and Th2 Responses in Autoimmune Disease --; Manipulation of the Th Responses of Oral Tolerance.

Text of Note

The two major subsets of CD4+ helper T cells, designated Th1 and Th2, have quite different patterns of cytokine production and, as a consequence, have very different roles in immune responses. The articles in this volume review both basic and clinical studies of T cell heterogeneity, including: - The mechanisms by which Th1 and Th2 cells develop and maintain their differences in cytokine production - The different roles of Th1 and Th2 cells in allergy, autoimmunity and infectious diseases - The prospects and strategies for therapeutic manipulation of Th1 and Th2 cells - The control of Th1 and Th2 responses by regulatory T cell subsets. The volume will give the reader a current view of the development and function of Th1 and Th2 cells and the attempts to treat immunological diseases with therapies directed towards altering the Th1/Th2 balance.

Immunology.

Medicine.

Oncology.

Class number

Book number

edited by Robert L. Coffman, Sergio Romagnani.

Robert L Coffman

S Romagnani

Electronic name

[Book]

Y