Rb as a positive transcriptional regulator during epithelial differentiation / Chantal E. Crémisi and Linda L. Pritchard -- pRb in the differentiation of normal and neoplastic cells / Deborah Pajalunga, Grazia Camarda and Marco Crescenzi -- Regulation of DNA replication by the retinoblastoma tumor suppressor protein / Erik S. Knudsen and Steven P. Angus -- New insights into transcriptional regulation by Rb : one size no longer fits all / Peggy J. Farnham -- Regulation of Rb function by noncyclin dependent kinases / Jaya Padmanabhan and Srikumar P. Chellappan -- Diverse regulatory functions of the E2F family of transcription factors / Fred Dick and Nicholas Dyson -- Regulation of E2F-responsive genes through histone modifications / Estelle Nicolas, Laetitia Daury and Didier Trouche -- Emerging roles for the retinoblastoma gene family / Jacqueline L. Vanderluit, Kerry L. Ferguson and Ruth S. Slack -- Rb and cellular differentiation / Lucia Latella and Pier Lorenzo Puri.