Nitrogen-15 and carbon-13 NMR studies of the interaction of cyanide ion with gold(I) drugs
نام عام مواد
[Thesis]
نام نخستين پديدآور
I. H. Ghazi
وضعیت نشر و پخش و غیره
نام ناشر، پخش کننده و غيره
King Fahd University of Petroleum and Minerals (Saudi Arabia)
تاریخ نشرو بخش و غیره
1993
مشخصات ظاهری
نام خاص و کميت اثر
124
یادداشتهای مربوط به پایان نامه ها
جزئيات پايان نامه و نوع درجه آن
M.S.
کسي که مدرک را اعطا کرده
King Fahd University of Petroleum and Minerals (Saudi Arabia)
امتياز متن
1993
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
N NMR studies of the interaction of N cyanide ion with gold(I)thiomalate (Autm) and gold(I)thioglucose (Autg) have been carried out at pH* 7.40. The chemical shifts of the two N containing species usd\rm Au(C\spN)\sb2\sp-usd and RS-Au-CN (where RS = tm or tg were identified. From the broadened N NMR signals, approximate lifetimes of the RS-Au-CN species were calculated. Captopril (Hcap) with gold(I) forms a 1:1 crystalline complex Au(I)cap. The exchange reactions of thiomalate and cyanide with Au(I)cap have been studied using C NMR spectroscopy. Au(I)cap forms a very high molecular weight polymer. Thiomalate and CN both bind to Au(I)cap, however, as expected, CN binds more strongly. Both the cis and trans Au(I)cap isomers were observed upon the addition of CN to A(I)cap solution. The ligand scrambling reaction of usd\rm R\sb3PAuC\spNusd to form (R3P)2Au and usd\rm Au(C\spN)\sb2\sp-usd has been studied for R = Me, Et, i-Pr, and Ph. Two P NMR resonances were observed for usd\rm R\sb3PAuCNusd and usd\rm(R\sb3P)\sb2Au\sp+usd species. However, for the N NMR, apart from usd\rm Et\sb3PAuC\spN,usd where two resonances were detected, only one averaged resonances observed for usd\rm R\sb3PAuC\spNusd (R = Me, Ph).
موضوع (اسم عام یاعبارت اسمی عام)
موضوع مستند نشده
Analytical chemistry
موضوع مستند نشده
Chemistry
موضوع مستند نشده
Chemistry
موضوع مستند نشده
Pure sciences
نام شخص به منزله سر شناسه - (مسئولیت معنوی درجه اول )