Novel roles for ferrocene derivatives in molecular recognition
نام عام مواد
[Thesis]
نام نخستين پديدآور
J. C. Medina
نام ساير پديدآوران
G. W. Gokel
وضعیت نشر و پخش و غیره
نام ناشر، پخش کننده و غيره
University of Miami
تاریخ نشرو بخش و غیره
1992
مشخصات ظاهری
نام خاص و کميت اثر
206
یادداشتهای مربوط به پایان نامه ها
جزئيات پايان نامه و نوع درجه آن
Ph.D.
کسي که مدرک را اعطا کرده
University of Miami
امتياز متن
1992
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
The first chapter deals with the syntheses and characterization of the cation binding properties of several ferrocenyl ionophore compounds. Special interest was given to ferrocenydimethyl-(2.2) -cryptand which possess extraordinary cation binding abilities. The cation-ionophore interactions of this compound were studied by H, C, and Na NMR spectroscopy, UV-Visible spectroscopy, fast atom bombardment mass spectroscopy, X-ray analysis, cyclic voltammetry, and ion selective electrode techniques. Evidence for the role of iron as a donor group was found using these techniques. The strong cation stabilizing properties of ferrocenyldimethyl-(2.2) -cryptand allowed for the first time the use of a redox switchable ionophore in the determination of cations in water. In chapter two we discuss the syntheses and properties of a novel family of molecular receptors designed to bind small molecules. The X-ray analysis of the structure of one of the analogs show some degree of preorganization. H NMR techniques were employed to assess the extent of complexation exhibited by these receptors. In these molecules the ferrocene is used as an "atomic ball bearing" because of the small rotation energy of the cyclopentadiene rings. In the last chapter we discuss a novel family of ferrocenyl surfactants. Ferrocene is a neutral molecule of low polarity, however, when oxidized it becomes a ferrociniun cation. This positively charged molecule can serve as the polar head in our family of amphipathic compounds. It was demonstrated that ferrocenylmethyl dihydrocholesteryl ether did not aggregate when the molecule was in its neutral state, however, once oxidized it aggregated into irregular multilamellar vesicles as determined by electron microscopy and dynamic light scattering experiments. This constitutes the first case of electrochemically switchable vesicles.
موضوع (اسم عام یاعبارت اسمی عام)
موضوع مستند نشده
Applied sciences
موضوع مستند نشده
Chemical engineering
موضوع مستند نشده
Organic chemistry
موضوع مستند نشده
Pure sciences
موضوع مستند نشده
redox switching
نام شخص به منزله سر شناسه - (مسئولیت معنوی درجه اول )