عنوان

New strategies in stroke intervention :

شابک

1607612798

شابک

1607612801

شابک

9781607612797

شابک

9781607612803

شابک اشتباه

1607612798

شابک اشتباه

9781607612797

شماره

b791906

عنوان اصلي

New strategies in stroke intervention :

نام عام مواد

[Book]

ساير اطلاعات عنواني

ionic transporters, pumps, and new channels /

نام نخستين پديدآور

edited by Lucio Annunziato.

محل نشرو پخش و غیره

Totowa, N.J. :

نام ناشر، پخش کننده و غيره

Humana,

تاریخ نشرو بخش و غیره

©2009.

نام خاص و کميت اثر

1 online resource

عنوان فروست

Contemporary neuroscience

متن يادداشت

Includes bibliographical references and index.

متن يادداشت

Basis of Ionic Dysregulation in Cerebral Ischemia -- Why have Ionotropic and Metabotropic Glutamate Antagonists Failed in Stroke Therapy? -- Mitochondrial Channels as Potential Targets for Pharmacological Strategies in Brain Ischemia -- Endoplasmic Reticulum Calcium Homeostasis and Neuronal Pathophysiology of Stroke -- The Na + /Ca 2+ Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia -- The "Loop" Diuretic Drug Bumetanide-Sensitive Na + -K + -Cl -- Cotransporter in Cerebral Ischemia -- The Na + /H + Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia -- The Na + /K + -ATPase as a Drug Target for Ischemic Stroke -- Acid-Sensing Ion Channels (ASICs): New Targets in Stroke Treatment -- Role of TRPM7 in Ischemic CNS Injury -- Subtypes of Voltage-Gated Ca 2+ Channels and Ischemic Brain Injury -- The Diverse Roles of K + Channels in Brain Ischemia -- Clinical Trials with Drugs Targeting Ionic Channels, Antiporters, and Pumps in Ischemic Stroke.

بدون عنوان

0

متن يادداشت

Ischemic brain damage represents a major source of morbidity and mortality in westernized society and poses a significant financial burden on the health care system. To date, few effective therapies have been realized to treat stroke and promising avenues have not proven clinically useful. Recent evidence, however, suggests that channels, pumps, and ionic exchangers are involved in CNS ischemia and ischemic stroke, but the potential contribution of these channels for curing stroke is far less understood than for many other normal and pathological conditions. New Strategies in Stroke Intervention: Ionic Channels, Pumps, and Transporters analyzes the roles played by targets in stroke development and the potential action of drugs modulating these proteins. This book provides a groundbreaking review of these ionic channels, pumps, and transporters as regulators of neuronal ionic homeostasis, providing a better understanding of ischemic brain disorders and the new pharmacological avenues for a cure. It will be a useful tool for researchers working in this field, and any student interested in the physiological, pathophysiological, and pharmacological features of stroke damage. About the Editor: Lucio Annunziato is a professor of pharmacology in the School of Medicine at the University of Naples ''Federico II'', Italy. He is coordinator of the University's neuroscience Ph. D. program and director of the Department of Neuroscience. He is also the president elect of the Italian Society of Neuroscience. Dr. Annunziato has authored more than 150 full papers and his scientific interest is mainly devoted to the molecular pharmacology of plasma membrane transporters and ionic channels involved in the pathophysiology of stroke. Most of his recent papers have appeared in the most qualified international journals in the field of ischemic neurodegeneration.

منبع سفارش / آدرس اشتراک

Springer

شماره انبار

978-1-60761-279-7

عنوان

New strategies in stroke intervention.

شماره استاندارد بين المللي کتاب و موسيقي

1607612798

موضوع مستند نشده

Cerebrovascular disease-- Treatment.

موضوع مستند نشده

Brain-- drug effects.

موضوع مستند نشده

Ion Channels-- therapeutic use.

موضوع مستند نشده

Ion Pumps-- therapeutic use.

موضوع مستند نشده

Stroke-- drug therapy.

موضوع مستند نشده

Biomédecine.

موضوع مستند نشده

Cerebrovascular disease-- Treatment.

موضوع مستند نشده

MEDICAL-- Neurology.

موضوع مستند نشده

Sciences de la vie.

موضوع مستند نشده

MED-- 056000

شماره

ويراست

شماره رده

نشانه اثر

شماره رده

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

Annunziato, Lucio.

تاريخ عمليات

20201207051035.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y