عنوان

Nonviral vectors for gene therapy :

شابک

0896037126

شابک

1592591396

شابک

9780896037120

شابک

9781592591398

شماره

b782920

عنوان اصلي

Nonviral vectors for gene therapy :

نام عام مواد

[Book]

ساير اطلاعات عنواني

methods and protocols /

نام نخستين پديدآور

edited by Mark A. Findeis.

محل نشرو پخش و غیره

Totowa, N.J. :

نام ناشر، پخش کننده و غيره

Humana Press,

تاریخ نشرو بخش و غیره

©2001.

نام خاص و کميت اثر

1 online resource (xi, 399 pages) :

ساير جزييات

illustrations

عنوان فروست

Methods in molecular medicine ;

مشخصه جلد

65

متن يادداشت

Includes bibliographical references and index.

متن يادداشت

""Nonviral Vectors for Gene Therapy""; ""Preface""; ""Contents""; ""Contributors""; ""1 Synthesis of Polyampholyte Comb-Type Copolymers Consisting of Poly(L-lysine) Backbone and Hyaluronic Acid Side Chains for DNA Carrier""; ""2 Cationic alpha-Helical Peptides for Gene Delivery into Cells""; ""3 Supramolecular Self-Assembly of Poly(ethylene glycol)-Block-Poly(L-lysine) Dendrimer with Plasmid DNA""; ""4 Water-Soluble Cationic Methacrylate Polymers for Nonviral Gene Delivery""; ""5 Stabilization of Polycation�DNA Complexes by Surface Modification with Hydrophilic Polymers""

متن يادداشت

""13 Rapid and Systematic Transfer and Recovery of Large BACs/PACs into Mammalian Cells by HAEC Retrofitting""""14 Systemic Delivery of Therapeutic Proteins by Intramuscular Injection of Plasmid DNA""; ""15 Local Delivery of Therapeutic Proteins by Intratumoral Injection of Plasmid DNA�Lipid Complexes""; ""16 Nonviral DNA Delivery from Polymeric Systems""; ""17 Promotion of Duplex and Triplex DNA Formation by Polycation Comb-Type Copolymers""; ""18 Lyophilization of Nonviral Gene Delivery Systems""

متن يادداشت

""19 Ultraviolet Absorption and Circular Dichroism Spectroscopy of Nonviral Gene Delivery Complexes""""20 Characterization of Synthetic Gene Delivery Vectors by Infrared Spectroscopy""; ""21 Characterization of Cationic Vector-Based Gene Delivery Vehicles Using Isothermal Titration and Differential Scanning Calorimetry""; ""22 Light-Scattering Techniques for Characterization of Synthetic Gene Therapy Vectors""; ""23 Renal Gene Therapy""; ""Index""

متن يادداشت

""6 Use of Disulfide Cationic Lipids in Plasmid DNA Delivery""""7 Interactions of Lipid�Oligonucleotide Conjugates with Low-Density Lipoprotein""; ""8 Coupling of Nuclear Localization Signals to Plasmid DNA""; ""9 Progress Toward a Synthetic Virus: A Multicomponent System for Liver-Directed DNA Delivery""; ""10 Characterization of Polyampholyte Comb-Type Copolymer DNA Carriers""; ""11 Methods for Studying Formation of Polycation�DNA Complexes and Properties Useful for Gene Delivery""; ""12 Characterization of DNA Condensates by Atomic Force Microscopy""

بدون عنوان

0

بدون عنوان

8

بدون عنوان

8

بدون عنوان

8

متن يادداشت

Nonviral gene therapy-an emerging field with great clinical promise-avoids many problems associated with viral gene therapy and offers the possibility of superior clinical effectiveness. In Nonviral Vectors for Gene Therapy: Methods and Protocols, Mark A. Findeis has assembled a panel of active researchers to present their best methods not only for preparing, handling, and characterizing gene delivery agents, but also for gene delivery. To help those preparing and characterizing gene transfer agents, the contributors examine a broad range of compounds that bind with DNA to form the compact complexes that facilitate cellular delivery-among them peptide conjugates, synthetic polymers, and lipids. They also outline specific approaches to gene transfer in vivo, including direct delivery by intratumoral injection and indirect delivery by cell-specific targeting of DNA complexes, and discuss in detail many spectroscopic techniques for characterizing nonviral gene delivery agents. Opportunities for the development and application of these novel vectors in the research lab and eventually, in the clinic, are highlighted. Comprehensive and state-of-the-art, Nonviral Vectors for Gene Therapy: Methods and Protocols illuminates for today's investigators the powerful new approaches to the creation of nonviral materials, as well as their efficacious use in delivering therapeutic genes to patients across the spectrum of human disease.

متن يادداشت

Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.

عنوان

Nonviral vectors for gene therapy

عنوان

Springer Protocols

موضوع مستند نشده

Gene therapy, Laboratory manuals.

موضوع مستند نشده

Genetic vectors, Laboratory manuals.

موضوع مستند نشده

Analytical, Diagnostic and Therapeutic Techniques and Equipment

موضوع مستند نشده

Biological Therapy.

موضوع مستند نشده

Drug Delivery Systems.

موضوع مستند نشده

Drug Therapy.

موضوع مستند نشده

Gene Transfer Techniques.

موضوع مستند نشده

Genetic Engineering.

موضوع مستند نشده

Genetic Phenomena.

موضوع مستند نشده

Genetic Structures.

موضوع مستند نشده

Genetic Techniques.

موضوع مستند نشده

Genetic Therapy.

موضوع مستند نشده

Genetic Vectors.

موضوع مستند نشده

Investigative Techniques

موضوع مستند نشده

Methods.

موضوع مستند نشده

Phenomena and Processes

موضوع مستند نشده

Therapeutics.

موضوع مستند نشده

Health & Biological Sciences.

موضوع مستند نشده

Medicine.

موضوع مستند نشده

Pathology.

موضوع مستند نشده

Gene therapy.

موضوع مستند نشده

Genetic vectors.

موضوع مستند نشده

Gentherapie.

موضوع مستند نشده

HEALTH & FITNESS-- Diseases-- Genetic.

موضوع مستند نشده

MEDICAL-- Genetics.

موضوع مستند نشده

Wetenschappelijke technieken.

موضوع مستند نشده

HEA-- 039060

موضوع مستند نشده

MED-- 107000

موضوع مستند نشده

PSF.

شماره

ويراست

شماره رده

نشانه اثر

شماره رده

شماره رده

نشانه اثر

کد سيستم

مستند نام اشخاص تاييد نشده

Findeis, Mark A.

تاريخ عمليات

20201206212245.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y