عنوان

Platinum-based drugs in cancer therapy /

شابک

0585395136

شابک

1592590128

شابک

9780585395135

شابک

9781592590124

شابک اشتباه

0896035999

شابک اشتباه

9780896035997

شماره

b758033

عنوان اصلي

Platinum-based drugs in cancer therapy /

نام عام مواد

[Book]

نام نخستين پديدآور

edited by Lloyd R. Kelland and Nicholas P. Farrell.

محل نشرو پخش و غیره

Totowa, N.J. :

نام ناشر، پخش کننده و غيره

Humana Press,

تاریخ نشرو بخش و غیره

©2000.

نام خاص و کميت اثر

1 online resource (xii, 341 pages) :

ساير جزييات

illustrations

عنوان فروست

Cancer drug discovery and development ;

مشخصه جلد

7

متن يادداشت

Includes bibliographical references and index.

متن يادداشت

I: Platinum Chemistry -- 1 The Chemistry of Cisplatin in Aqueous Solution -- 2 Chemistry and Structural Biology of 1,2-Interstrand Adducts of Cisplatin -- 3 Transplatin-Modified Oligonucleotides as Potential Antitumor Drugs -- II: Platinum Biochemistry -- 4 Cisplatin Accumulation -- 5 Cisplatin Resistance in Ovarian Cancer: Mismatch Repairand Engagement of Apoptosis -- 6 DNA Adduct Tolerance and Bypass -- 7 How Does Cisplatin Kill Cells? -- III: Clinical Antitumor Activity and Toxicology of Platinum Drugs -- 8 Clinical Experience with Cisplatin and Carboplatin -- 9 Clinical Experience: Platinum and Taxanes -- 10 Clinical Experience: DACH-Based Platinum Drugs -- 11 Clinical Toxicology of Platinum-Based Cancer Chemotherapeutic Agents -- 12 Toxicology and Regulatory Aspects of Platinum Drugs -- IV: New Platinum Drugs of the Future -- 13 New Platinum Drugs: The Pathway to Oral Therapy -- 14 Polynuclear Charged Platinum Compounds as a New Class of Anticancer Agents: Toward a New Paradigm.

بدون عنوان

0

متن يادداشت

In Platinum-Based Drugs in Cancer Therapy, leading international experts comprehensively review all aspects of platinum anticancer drugs and their current use in treatment, as well as examining their future therapeutic prospects. Writing from a variety of disciplines, these authorities discuss the chemistry of cisplatin in aqueous solution, the molecular interaction of platinum drugs with DNA, and such exciting new areas as DNA mismatch repair, replicative bypass, apoptosis, and the transport of platinum drugs into tumor cells. The antitumor activity and toxicology of platinum-based drugs is also addressed in a thorough discussion of the clinical experience with cisplatin and carboplatin, including their promising recent combinations with taxanes and oxaliplatin. The emergent platinum drugs of the future-orally active agents, the sterically hindered ZD0473, and the polynuclear charged platinum BBR3464-are also fully considered. Timely and interdisciplinary, Platinum-Based Drugs in Cancer Therapy offers cancer therapeutics specialists an illuminating survey of every aspect of platinum drugs from mechanisms of action to toxicology, tumor resistance, and new analogs. This important book captures the essence of the fresh clinical possibilities now strongly emerging thirty years after cisplatin's discovery.

متن يادداشت

Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.

عنوان

Platinum-based drugs in cancer therapy.

شماره استاندارد بين المللي کتاب و موسيقي

0896035999

موضوع مستند نشده

Cancer-- Chemotherapy.

موضوع مستند نشده

Antineoplastic Agents.

موضوع مستند نشده

Cisplatin.

موضوع مستند نشده

Neoplasms-- drug therapy.

موضوع مستند نشده

Platinum Compounds-- therapeutic use.

موضوع مستند نشده

Cancer-- Chimiothérapie.

موضوع مستند نشده

Cisplatine.

موضوع مستند نشده

Platine-- Emploi en thérapeutique.

موضوع مستند نشده

ADN-- Réparation.

موضوع مستند نشده

Antinéoplasiques.

موضوع مستند نشده

Cancer-- Chemotherapy.

موضوع مستند نشده

Carboplatine.

موضوع مستند نشده

Cisplatine.

موضوع مستند نشده

Cisplatine.

موضوع مستند نشده

Composés du platine-- usage thérapeutique.

موضوع مستند نشده

HEALTH & FITNESS-- Diseases-- Cancer.

موضوع مستند نشده

MEDICAL-- Oncology.

موضوع مستند نشده

Oxaliplatine.

موضوع مستند نشده

Tumeurs-- Traitement médicamenteux.

موضوع مستند نشده

HEA-- 039030

موضوع مستند نشده

MED-- 062000

موضوع مستند نشده

MJCL

موضوع مستند نشده

MJCL

شماره

ويراست

شماره رده

نشانه اثر

شماره رده

مستند نام اشخاص تاييد نشده

Farrell, Nicholas,1948-

مستند نام اشخاص تاييد نشده

Kelland, Lloyd R.

تاريخ عمليات

20201204180830.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y