عنوان

Cancer susceptibility :

شابک

1607617595

شابک

9781607617594

شابک اشتباه

1607617587

شابک اشتباه

9781607617587

شماره

b716329

عنوان اصلي

Cancer susceptibility :

نام عام مواد

[Book]

ساير اطلاعات عنواني

methods and protocols /

نام نخستين پديدآور

volume editor, Michelle Webb.

محل نشرو پخش و غیره

London :

نام ناشر، پخش کننده و غيره

Springer [distributor],

تاریخ نشرو بخش و غیره

2010.

نام خاص و کميت اثر

1 online resource

عنوان فروست

Methods in molecular biology ;

مشخصه جلد

653

متن يادداشت

Includes bibliographical references and index.

متن يادداشت

The identification of colon cancer susceptibility genes by using genome-wide scans -- Prioritizing candidate genetic modifiers of BRCA1 and BRCA2 using a combinatorial analysis of global expression and polymorphism association studies of breast cancer -- Microarray-based comparative genomic hybridization (array-CGH) as a useful tool for identifying genes involved in Glioblastoma (GB) -- Multiplex Amplifiable Probe Hybridization (MAPH) methodology as an alternative to comparative genomic hybridization (CGH) -- Utilizing Saccharomyces cerevisiae to identify aneuploidy and cancer susceptibility genes -- Computational identification of cancer susceptibility loci -- Digital candidate gene approach (DigiCGA) for identification of cancer genes -- The use of denaturing high performance liquid chromatography (DHPLC) for mutation scanning of hereditary cancer genes -- Enhanced mismatch mutation analysis: simultaneous detection of point mutations and large scale rearrangements by capillary electrophoresis, application to BRCA1 and BRCA2 -- Economical protocol for combined single-strand conformation polymorphism and heteroduplex analysis on a standard capillary electrophoresis apparatus -- Mutational screening of hMLH1 and hMSH2 that confer inherited colorectal cancer susceptibility using denature gradient gel electrophoresis (DGGE) -- s-RT-MELT: a novel technology for mutation screening -- Zoom-in array comparative genomic hybridization (aCGH) to detect germline rearrangements in cancer susceptibility genes -- Development of a scoring system to screen for BRCA1/2 mutations -- Use of splicing reporter minigene assay to evaluate the effect on splicing of unclassified genetic variants -- Functional analysis of human BRCA2 variants using a mouse embryonic stem cell-based assay -- Developing functional assays for BRCA1 unclassified variants.

بدون عنوان

0

متن يادداشت

Over the past two decades, spectacular advances have been made in our understanding of the molecular genetics of cancer, leading to the pursuit of identifying genes that, when mutated, result in an increased susceptibility to the disease. In Cancer Susceptibility: Methods and Protocols, experts in the field bring together the most recent technological developments for identifying and screening cancer susceptibility genes. Divided into two clear sections, the book begins with gene identification, which updates and informs scientists working at identifying novel cancer susceptibility genes, while the second part deals with mutation screening technologies that aid scientists and clinicians working to translate this knowledge into the clinic. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Susceptibility: Methods and Protocols is a timely collection that seeks to provide researchers with the tools to predict and combat this terrible disease.

منبع سفارش / آدرس اشتراک

Springer

شماره انبار

978-1-60761-758-7

عنوان

Cancer susceptibility.

شماره استاندارد بين المللي کتاب و موسيقي

1607617587

موضوع مستند نشده

Cancer-- Genetic aspects.

موضوع مستند نشده

Cancer-- Susceptibility.

موضوع مستند نشده

Analytical, Diagnostic and Therapeutic Techniques and Equipment

موضوع مستند نشده

Biological Science Disciplines.

موضوع مستند نشده

Biology.

موضوع مستند نشده

Community Health Services.

موضوع مستند نشده

Delivery of Health Care.

موضوع مستند نشده

Diagnosis.

موضوع مستند نشده

Diagnostic Services.

موضوع مستند نشده

Diagnostic Techniques and Procedures.

موضوع مستند نشده

Disciplines and Occupations

موضوع مستند نشده

Disease Attributes

موضوع مستند نشده

Disease Susceptibility.

موضوع مستند نشده

Disease.

موضوع مستند نشده

Genetic Phenomena.

موضوع مستند نشده

Genetic Predisposition to Disease.

موضوع مستند نشده

Genetic Services.

موضوع مستند نشده

Genetic Techniques.

موضوع مستند نشده

Genetic Testing.

موضوع مستند نشده

Genetics.

موضوع مستند نشده

Genotype.

موضوع مستند نشده

Health Care Facilities, Manpower, and Services

موضوع مستند نشده

Health Services.

موضوع مستند نشده

Investigative Techniques

موضوع مستند نشده

Laboratory Manuals

موضوع مستند نشده

Methods.

موضوع مستند نشده

Natural Science Disciplines.

موضوع مستند نشده

Pathologic Processes.

موضوع مستند نشده

Pathological Conditions, Signs and Symptoms

موضوع مستند نشده

Phenomena and Processes

موضوع مستند نشده

Preventive Health Services.

موضوع مستند نشده

Publication Characteristics

موضوع مستند نشده

Publication Formats

موضوع مستند نشده

Cancer-- Genetic aspects.

موضوع مستند نشده

Cancer-- Susceptibility.

موضوع مستند نشده

Health & Biological Sciences.

موضوع مستند نشده

Medicine.

موضوع مستند نشده

Oncology.

موضوع مستند نشده

MED062000

موضوع مستند نشده

MJCL

شماره

ويراست

شماره رده

نشانه اثر

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

Webb, Michelle.

تاريخ عمليات

20201208085150.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y