عنوان

The relationships between West Nile and Kunjin viruses.

شماره

LA0wn413qk

عنوان اصلي

The relationships between West Nile and Kunjin viruses.

نام عام مواد

[Article]

نام نخستين پديدآور

Scherret, J. H.; Poidinger, M.; Mackenzie, J. S.; Broom, A. K.; Deubel, V.; Lipkin, W. I.; Briese, T.; Gould, E. A.; Hall, R. A.

متن يادداشت

Until recently, West Nile (WN) and Kunjin (KUN) viruses were classified as distinct types in the Flavivirus genus. However, genetic and antigenic studies on isolates of these two viruses indicate that the relationship between them is more complex. To better define this relationship, we performed sequence analyses on 32 isolates of KUN virus and 28 isolates of WN virus from different geographic areas, including a WN isolate from the recent outbreak in New York. Sequence comparisons showed that the KUN virus isolates from Australia were tightly grouped but that the WN virus isolates exhibited substantial divergence and could be differentiated into four distinct groups. KUN virus isolates from Australia were antigenically homologous and distinct from the WN isolates and a Malaysian KUN virus. Our results suggest that KUN and WN viruses comprise a group of closely related viruses that can be differentiated into subgroups on the basis of genetic and antigenic analyses.

تاريخ نشر

2001

عنوان

UC Irvine

نام الکترونيکي

نوع ماده

[Article]

کد کاربرگه

275578

سطح دسترسي

a

تكميل شده

Y