عنوان

Chromosome translocation /

شابک

9789811305931

شابک

9811305935

شابک اشتباه

9789811305924

شابک اشتباه

9811305927

عنوان اصلي

Chromosome translocation /

نام عام مواد

[Book]

نام نخستين پديدآور

Yu Zhang, editor.

محل نشرو پخش و غیره

Singapore :

نام ناشر، پخش کننده و غيره

Springer,

تاریخ نشرو بخش و غیره

[2018]

تاریخ نشرو بخش و غیره

©2018

نام خاص و کميت اثر

1 online resource (v, 168 pages) :

ساير جزييات

illustrations (some color)

عنوان فروست

Advances in experimental medicine and biology,

مشخصه جلد

volume 1044

شاپا ي ISSN فروست

2214-8019 ;

متن يادداشت

Includes bibliographical references.

متن يادداشت

Historical and clinical perspectives on chromosomal translocations / Ellen S. Wilch, Cynthia C. Morton -- Induction of chromosomal translocations with CRISPR-Cas9 and other nucleases: understanding the repair mechanisms that give rise to translocations / Erika Brunet, Maria Jasin -- Dynamics of double-strand breaks: implications for the formation of chromosome translocations / Henrike Johanna Gothe, Vera Minneker, Vassilis Roukos -- The CRISPR/Cas9 system as a tool to engineer chromosomal translocation in vivo / Taek-Chin Cheong, Rafael B. Blasco, Roberto Chiarle -- Generation of genomic alteration from cytidine deamination / Xiaojing Liu, Fei-Long Meng -- The role for the DSB response pathway in regulating chromosome translocations / Rajib Ghosh, Debamitra Das, Sonia Franco -- Telomeres and chromosomal translocations / Duncan M. Baird, Eric A. Hendrickson -- 3D genome organization influences the chromosome translocation pattern / Rachel Patton McCord, Adayabalam Balajee -- The role of chromosome deletions in human cancers / Mei Chen, Yi Yang, Yu Liu, Chong Chen -- Processing-challenges generated by clusters of DNA double-strand breaks underpin increased effectiveness of high-LET radiation and chromothripsis / Emil Mladenov, Janapriya Saha, George Iliakis.

بدون عنوان

0

متن يادداشت

"This volume discusses various aspects of mechanisms and methodologies of chromosome translocations, ranging from a historical and clinical overview of chromosome translocations to the rapid development of the next-generation sequencing technologies, which has dramatically increased our understanding of the spectrum of chromosome translocations in human diseases. The book also introduces the mechanistic studies on chromosome deletions and their implications in cancer, and discusses the mechanisms of regulating chromothripsis, a unique complex type of chromosome translocation"--Publisher's description.

منبع سفارش / آدرس اشتراک

Springer Nature

شماره انبار

com.springer.onix.9789811305931

عنوان

Chromosome translocation.

شماره استاندارد بين المللي کتاب و موسيقي

9789811305924

موضوع مستند نشده

Translocation (Genetics)

موضوع مستند نشده

Translocation, Genetic-- physiology.

موضوع مستند نشده

SCIENCE-- Life Sciences-- Biochemistry.

موضوع مستند نشده

Translocation (Genetics)

موضوع مستند نشده

MFN

موضوع مستند نشده

SCI-- 007000

شماره

ويراست

شماره رده

شماره رده

مستند نام اشخاص تاييد نشده

Zhang, Yu

تاريخ عمليات

20200823223933.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y