یادداشتهای مربوط به کتابنامه ، واژه نامه و نمایه های داخل اثر
متن يادداشت
Includes bibliographical references (pages 161-170) and index.
یادداشتهای مربوط به مندرجات
متن يادداشت
Introduction -- Early pioneers -- Amending the central dogma -- The origin of retroviruses -- Retroviruses and evolution -- Revealing the genetic basis of cancer -- HIV and the AIDS pandemic -- Epilogue.
بدون عنوان
0
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
When invading a host cell, viruses seize cell machinery to make copies of their own genes. The immune system recognizes the invasion. In contrast, retroviruses colonize host cells through the process of reverse transcriptase. Retroviruses open host cell DNA and graft in their retroviral RNA, integrating into the host genome. The immune system has difficulty recognizing or ridding of foreign DNA that has become its own. Discovering Retroviruses presents the history of retrovirus discovery. Skalka illuminates retroviruses' role in evolution, human health, and disease, from the first sighting at the end of the nineteenth century to recent use in genetic engineering. Retroviral sequences in the human genome mark sites where endogenous retrovirus integrated over six million years ago. The 100,000 pieces of retrovirus DNA are remnants from germ line cell invasions and total approximately eight percent of the human genome. Through investigation of animal and human retroviral sequences, we know retroviral mutations can lead to cancers and immunodeficiencies, including HIV and leukemia. Today, researchers harness retroviruses for use in gene delivery systems and precision medicine advances. Discovering Retroviruses offers a lively perspective on stories of the major pioneers of the past century and the extraordinary roads to their discoveries, and demonstrates the growing importance of genetics to modern biomedicine.--
موضوع (اسم عام یاعبارت اسمی عام)
موضوع مستند نشده
Medicine-- Research-- History.
موضوع مستند نشده
Retrovirus infections.
موضوع مستند نشده
Retroviruses.
موضوع مستند نشده
Viruses-- Evolution.
موضوع مستند نشده
Biomedical Research-- history.
موضوع مستند نشده
Oncogenic Viruses-- genetics.
موضوع مستند نشده
Retroviridae Infections.
موضوع مستند نشده
Retroviridae.
موضوع مستند نشده
Medicine-- Research.
موضوع مستند نشده
Retrovirus infections.
موضوع مستند نشده
Retroviruses.
موضوع مستند نشده
Viruses-- Evolution.
رده بندی ديویی
شماره
579
.
2/569
ويراست
23
رده بندی کنگره
شماره رده
QR414
.
5
نشانه اثر
.
S53
2018
سایر رده بندی ها
شماره رده
QW
168
.
5
.
R18
نام شخص به منزله سر شناسه - (مسئولیت معنوی درجه اول )