عنوان

Basic applied bioinformatics /

شابک

1119244331

شابک

1119244374

شابک

1119244412

شابک

9781119244332

شابک

9781119244370

شابک

9781119244417

شابک اشتباه

9781119244332

عنوان اصلي

Basic applied bioinformatics /

نام عام مواد

[Book]

نام نخستين پديدآور

Chandra Sekhar Mukhopadhyay, Ratan Kumar Choudhary, Mir Asif Iquebal ; with contributions from Ravi GVPPS Kumar [and 8 others].

محل نشرو پخش و غیره

Hoboken, NJ :

نام ناشر، پخش کننده و غيره

John Wiley & Sons, Inc.,

تاریخ نشرو بخش و غیره

2018.

تاریخ نشرو بخش و غیره

©2018

نام خاص و کميت اثر

1 online resource

متن يادداشت

Includes bibliographical references and index.

متن يادداشت

Section I: Molecular sequences and structures. Retrieval of sequence(s) from the NCBI Nucleotide database -- Retrieval of protein sequence from UniProtKB -- Downloading protein structure -- Visualizing protein structure -- Sequence format conversion -- Nucleotide sequence analysis using sequence manipulation suite (SMS) -- Detection of restriction enzyme sites -- Section II: Sequence alignment. dot plot analysis -- Needleman-Wunsch algorithm (global alignment) -- Smith-Waterman algorithm (local alignment) -- Sequence alignment using online tools -- Section III: Basic local alignment search tools. Basic local alignment search tool for Nucleotide (BLASTn) -- Basic local alignment search tool for amino acid sequences (BLASTp) -- BLASTx -- tBLASTn -- tBLASTx -- Section IV: Primer designing and quality checking. Primer designing: basics -- Designing PCR primers using the Primer3 online tool -- Quality checking of the designed primers -- Primer designing for SYBR green chemistry of qPCR -- Section V: Molecular phylogenetics. Construction of phylogenetic tree: unweighted‐pair group method with arithmetic mean (UPGMA) -- Construction of phylogenetic tree: Fitch Margoliash (FM) algorithm -- Construction of phylogenetic tree: neighbor‐joining method -- Construction of phylogenetic tree: maximum parsimony method -- Construction of phylogenetic tree: minimum evolution method -- Construction of phylogenetic tree using MEGA7 -- Interpretation of phylogenetic trees -- Section VI: Protein structure prediction. Prediction of secondary structure of protein -- Prediction of tertiary structure of protein: sequence homology -- Protein structure prediction using threading method -- Prediction of tertiary structure of protein: ab initio approach -- Validation of predicted tertiary structure of protein -- Section VII: Molecular docking and binding site prediction. Prediction of transcription binding sites -- Prediction of translation initiation sites -- Molecular docking -- Section VIII: Genome annotation. Genome annotation in prokaryotes -- Genome annotation in eukaryotes -- Section IX: Advanced biocomputational analyses. Concepts of real‐time PCR data analysis -- Overview of microarray data analysis -- Single nucleotide polymorphism (SNP) mining tools -- In silico mining of simple sequence repeats (SSR) markers -- Basics of RNA‐seq data analysis -- Functional annotation of common differentially expressed genes -- Identification of differentially expressed genes (DEGs) -- Estimating MicroRNA expression using the miRDeep2 tool -- miRNA target prediction -- Appendices. Usage of internet for bioinformatics -- important web resources for bioinformatics databases and tools -- NCBI database: a brief account -- EMBL databases and tools: an overview -- Basics of molecular phylogeny -- Evolutionary models of molecular phylogeny.

بدون عنوان

0

متن يادداشت

"An accessible guide that introduces students in all areas of life sciences to bioinformatics Basic Applied Bioinformatics provides a practical guidance in bioinformatics and helps students to optimize parameters for data analysis and then to draw accurate conclusions from the results. In addition to parameter optimization, the text will also familiarize students with relevant terminology. Basic Applied Bioinformatics is written as an accessible guide for graduate students studying bioinformatics, biotechnology, and other related sub-disciplines of the life sciences. This accessible text outlines the basics of bioinformatics, including pertinent information such as downloading molecular sequences (nucleotide and protein) from databases; BLAST analyses; primer designing and its quality checking, multiple sequence alignment (global and local using freely available software); phylogenetic tree construction (using UPGMA, NJ, MP, ME, FM algorithm and MEGA7 suite), prediction of protein structures and genome annotation, RNASeq data analyses and identification of differentially expressed genes and similar advanced bioinformatics analyses. The authors Chandra Sekhar Mukhopadhyay, Ratan Kumar Choudhary, and Mir Asif Iquebal are noted experts in the field and have come together to provide an updated information on bioinformatics. Salient features of this book includes: Accessible and updated information on bioinformatics tools A practical step-by-step approach to molecular-data analyses Information pertinent to study a variety of disciplines including biotechnology, zoology, bioinformatics and other related fields Worked examples, glossary terms, problems and solutions Basic Applied Bioinformatics gives students studying bioinformatics, agricultural biotechnology, animal biotechnology, medical biotechnology, microbial biotechnology, and zoology an updated introduction to the growing field of bioinformatics."--Publisher's description.

منبع سفارش / آدرس اشتراک

Safari Books Online

شماره انبار

CL0500000956

عنوان

Basic applied bioinformatics.

شماره استاندارد بين المللي کتاب و موسيقي

9781119244332

موضوع مستند نشده

Bioinformatics, Textbooks.

موضوع مستند نشده

Computational Biology.

موضوع مستند نشده

Bioinformatics.

موضوع مستند نشده

MEDICAL-- Biostatistics.

موضوع مستند نشده

SCIENCE-- Life Sciences-- Biochemistry.

موضوع مستند نشده

SCI-- 007000

شماره

ويراست

شماره رده

نشانه اثر

شماره رده

کد سيستم

مستند نام اشخاص تاييد نشده

Mukhopadhyay, Chandra Sekhar

مستند نام اشخاص تاييد نشده

Choudhary, Ratan Kumar

مستند نام اشخاص تاييد نشده

Iquebal, Mir Asif

تاريخ عمليات

20200822152821.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y