عنوان

Selected Topics in Mass Spectrometry in the Biomolecular Sciences

شابک

9401061718

شابک

9401151652

شابک

9789401061711

شابک

9789401151658

شماره

b595419

عنوان اصلي

Selected Topics in Mass Spectrometry in the Biomolecular Sciences

نام عام مواد

[Book]

نام نخستين پديدآور

edited by Richard M. Caprioli, Antonio Malorni, Giovanni Sindona.

محل نشرو پخش و غیره

Dordrecht

نام ناشر، پخش کننده و غيره

Springer Netherlands : Imprint : Springer

تاریخ نشرو بخش و غیره

1997

نام خاص و کميت اثر

(612 pages)

عنوان فروست

NATO ASI series., Series C,, Mathematical and physical sciences ;, 504.

متن يادداشت

I: Methods in Mass Spectrometry --; Electrospray Ionization: Theory and Application --; Atmospheric Pressure Ionization (ESI and APCI) Theory and Application --; Matrix-Assisted Laser Desorpition-Ionization (MALDI) Mass Spectrometry: Principles and Applications --; High Sensitivity ESI/MS and MALDI MS --; Optimised GC/MS Interfacing Systems and Operating Conditions --; Quantitative Analysis by Mass Spectrometry: Some Important Considerations --; Optimization of Mass Spectrometric Ionisation Efficiency Data --; Role of Internal Energy in Mass Spectrometric Fragmentation --; Interaction of Metal Ions and Protons with Simple Biomolecules. Structure Information from Bond Energies and Entropy Effects --; A Promising Marriage Between Theory and Experiment: Density Functional Method Versus Mass Spectrometry --; II: Instrumentation for Mass Analysis and Detection --; Recent Advances in Magnet Sector Mass Spectrometry --; Quadrupole Mass Filters and Quadrupole Ion Traps --; Time-of-Flight Mass Spectrometry --; Combined Analyzer Technologies --; Fourier Transform Mass Spectrometry --; III: Application to Biomolecules --; Protein Characterization by MS in Pharmaceutical Industry. Structural Characterization of Modified Forms of Recombinant Hirudin Sequence Variant 1 and Direct Batch Analysis --; Folding Pathways of Disulphide Containing Proteins --; Integration of Chemical Modification Reactions and Mass Spectrometric Methods in Protein Characterisation --; PSD-MALDI Analysis of Peptides --; Development of a Mass Spectrometric Approach for the Characterisation of Hemoglobin Adducts --; Reactivity of Antineoplastic Drugs with Model Peptides Studied by Advanced Mass Spectrometry Methodologies --; Applications of Mass Spectrometry in Biochemical Studies of Nucleosides, Nucleotides and Nucleic Acids --; MALDI Mass Analysis of Oligonucleotides --; DNA Adducts in Human Carcinogenesis. Clues to Etiology and Mechanism --; MALDI MS of Oligo and Polysaccharides --; Mass Spectrometry of Isoeicosanoids as Novel Lipid Substances --; The Role of Mass Spectrometry in the Characterization of Plant Metabolites from Crude Extracts --; Environmental Applications of Mass Spectrometry: Toxaphene Analysis --; The Determination of Polar Compounds in the Aquatic Environment --; Some Mass Spectrometry Contributions in the Study of Cultural Heritage.

متن يادداشت

Many fundamental aspects of the methods used in mass spectrometry are here presented by outstanding scientists, with reference to very recent developments. The principles and applications of electrospray, ion spray and MALDI ionization technique are presented, together with optimised GC/MS interfacing systems and tools for quantitative analysis. A comprehensive treatment of modern instrumentation for mass analysis and detection is also included. The major part of the book deals with bioanalytical applications to peptides, proteins, oligonucleotides, polysaccharides, lipids and plant metabolites. Several papers are devoted to the evaluation of adduct formation between DNA and carcinogens. Environmental applications are also included, with examples of some specific cases.
Fundamentals and applications are treated with the same degree of depth: the first two parts of the book therefore provide a basis for the understanding of the biomolecular applications section.
Audience: Ideal for advanced graduate students of chemistry who have learned some basic mass spectrometry. Also useful for Ph. D. students in chemistry, biology and medicine. Of value to researchers in academic and industrial laboratories.

عنوان اصلي به زبان ديگر

Proceedings of the NATO Advanced Study Institute on Mass Spectrometry in the Biomolecular Sciences, Altavilla-Milicia (PA), Italy, 7-18 July 1996

موضوع مستند نشده

Biomolecules -- Analysis -- Congresses.

موضوع مستند نشده

Biomolecules -- Analysis.

موضوع مستند نشده

Mass spectrometry -- Congresses.

مستند نام اشخاص تاييد نشده

edited by Richard M. Caprioli, Antonio Malorni, Giovanni Sindona.

مستند نام اشخاص تاييد نشده

Antonio Malorni

مستند نام اشخاص تاييد نشده

Giovanni Sindona

مستند نام اشخاص تاييد نشده

Richard M Caprioli

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y