عنوان

Specificity, Function, and Development of NK Cells :

شابک

3540639411

شابک

3642468594

شابک

9783540639411

شابک

9783642468599

شماره

b568396

عنوان اصلي

Specificity, Function, and Development of NK Cells :

نام عام مواد

[Book]

ساير اطلاعات عنواني

NK Cells: The Effector Arm of Innate Immunity

نام نخستين پديدآور

edited by Klas Kärre, Marco Colonna.

محل نشرو پخش و غیره

Berlin, Heidelberg

نام ناشر، پخش کننده و غيره

Springer Berlin Heidelberg

تاریخ نشرو بخش و غیره

1998

نام خاص و کميت اثر

(ix, 248 pages 22 illustrations)

عنوان فروست

Current topics in microbiology and immunology, 230.

متن يادداشت

A. NK Receptors and Coreceptors --; Regulation of Mouse NK Cells by Structurally Divergent Inhibitory Receptors --; Stimulatory Receptors in NK and T Cells --; Killer Cell Inhibitory Receptor Expression by T Cells --; The CD94/NKG2 C-Type Lectin Receptor Complex --; Triggering of Natural Killer Cell Mediated Cytotoxicity by Costimulatory Molecules --; Fc Receptors on Natural Killer Cells --; Adhesion in NK Cell Function --; B. Activation of NK Cells and Effector Functions --; Signal Transduction During NK Cell Activation: Balancing Opposing Forces --; Effector Pathways of Natural Killer Cells --; C. Development of NK Cells --; Toward a Quantitative Analysis of the Repertoire of Class I MHC-Specific Inhibitory Receptors on Natural Killer Cells --; Ontogeny and Differentiation of Murine Natural Killer Cells and Their Receptors --; D. Role of NK Cells in Infections and Tumors --; Control of Infections by NK Cells --; Natural Killer Cells and Tumor Therapy.

متن يادداشت

Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors.

موضوع مستند نشده

Immunology.

موضوع مستند نشده

Medicine.

موضوع مستند نشده

Oncology.

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

edited by Klas Kärre, Marco Colonna.

مستند نام اشخاص تاييد نشده

Klas Kärre

مستند نام اشخاص تاييد نشده

Marco Colonna

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y