عنوان

Leukolysins and Cancer

شابک

1461245869

شابک

9781461245865

شماره

b555192

عنوان اصلي

Leukolysins and Cancer

نام عام مواد

[Book]

نام نخستين پديدآور

edited by Janet H. Ransom, John R. Ortaldo.

محل نشرو پخش و غیره

Totowa, NJ

نام ناشر، پخش کننده و غيره

Humana Press

تاریخ نشرو بخش و غیره

1988

نام خاص و کميت اثر

(XVIII, 322 pages).

عنوان فروست

Contemporary biomedicine, 8.

متن يادداشت

1. Biology and Biochemistry --;Cytolytic Pore-Forming Proteins --;Cytolysin: Its Purification, Biological Properties, and Mechanisms of Action --;Monocyte Cytotoxic Factors --;Triggering of a Cytolytic Factor with TNF-Like Activity From Human Monocytes --;1. Introduction --;2. Results and Discussion --;2.3. Target-Cell Selectivity and Capacity to Induce CM Production in Monocytes --;References --;Antitumor Monocyte Cytotoxic Factors (MCF) Produced by Human Blood Monocytes: Production, Characterization, and Biological Significance --;1. Introduction --;2. Generation of MCF --;3. Lytic Activity of MCF --;4. Biochemical and Biophysical Characteristics of MCF --;5. Biological Significance of MCF --;6. Conclusion --;References --;Antiproliferative Effects of Interferon --;1. Introduction --;2. Structure of Interferon --;3. Interferon Receptors --;4. Mechanisms of Action --;5. In Vitro Antiproliferative Effects --;6. Structure-Function Relationships --;7. In Vivo Tumor Biology --;8. Conclusion --;References --;Natural Killer Cell Cytotoxic Factor --;Human and Rodent Natural Killer Cytotoxic Factors (NKCF): Characterization and Their Role in the NK Lytic Mechanism --;1. Introduction --;2. Materials and Methods --;3. Results and Discussion --;4. Concluding Remarks --;References --;Human Natural Killer Cytotoxic Factor (NKCF): Relevance, Mode of Action, and Relationship to Other Cytotoxic Factors --;1. Introduction --;2. Results --;3. Discussion --;References --;Natural Killer Cell Cytotoxic Factor --;1. Introduction --;2. Biology of NKCF --;3. Biochemistry of NKCF --;4. Mechanism of Action of NKCF --;5. Future Studies --;References --;Leukoregulin --;Leukoregulin: Biology, Biochemistry, and Mode of Action --;1. Introduction --;2. Biology of Leukoregulin --;3. Physicochemical Characteristics of Leukoregulin --;4. Conclusions --;References --;Leukoregulin Mechanisms of Anticancer Action --;1. Discovery of Leukoregulin --;2. Assays Defining Leukoregulin Activity --;3. Preparation of Leukoregulin --;4. Pathways of Leukoregulin Action --;5. Role of Leukoregulin in Homeostasis and Pathophysiology --;6. Therapeutic Implications and Research Directions --;References --;Lymphotoxins: Mediators of Cellular Activation, Inflammation, and Cell Lysis That Are Immunologically Related to Macrophage Toxins and Tumor Necrosis Factors --;1. Introduction --;2. Studies of Lymphotoxin from Normal Lymphocytes --;3. Immunological Relationships of LT-1, LT-2, LT-3, MCT, and TNF --;4. Effects of Lymphotoxins on Cells In Vitro --;5. Antitumor Effects of Lymphotoxins In Vivo --;6. Lymphotoxins as Inducers of Inflammation --;7. Conclusion --;References --;Tumor Necrosis Factors Alpha and Beta: A Family of Biochemically Related Cytokines --;1. History of Tumor Necrosis Factors --;2. Nomenclature: In Vivo Necrosis Activities --;3. HuTNF-? and HuTNF-?: Biochemistry and Molecular Biology --;4. Summary --;References --;2. Clinical Applications Interferons --;Clinical Aspects of Interferon Therapy in Human Cancer --;Antiproliferative and Clinical Antitumor Effects of Interferons --;Biologic Effects of Tumor Necrosis Factors Alpha and Beta --;Leukoregulin: Potential as a Clinical Cancer Therapeutic Agent.

متن يادداشت

This book is intended for both immunologists conducting basic research and clinical oncologists, since it reviews not only the clinical applications of the leukolysins, but presents a current update on those leukolysins that are in early developmental stages of research and could enter into clinical trials in a few years.

عنوان اصلي به زبان ديگر

Contemporary Biomedicine, vol. 8

موضوع مستند نشده

Leukolysins.

موضوع مستند نشده

Medicine.

موضوع مستند نشده

Oncology.

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

edited by Janet H. Ransom, John R. Ortaldo.

مستند نام اشخاص تاييد نشده

Janet H Ransom

مستند نام اشخاص تاييد نشده

John R Ortaldo

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y