عنوان

Initial Rate Enzyme Kinetics

شابک

3642809669

شابک

3642809685

شابک

9783642809668

شابک

9783642809682

شماره

b554518

عنوان اصلي

Initial Rate Enzyme Kinetics

نام عام مواد

[Book]

نام نخستين پديدآور

by Herbert J. Fromm.

محل نشرو پخش و غیره

Berlin, Heidelberg

نام ناشر، پخش کننده و غيره

Springer Berlin Heidelberg

تاریخ نشرو بخش و غیره

1975

عنوان فروست

Molecular biology, biochemistry, and biophysics, 22.

متن يادداشت

I Nomenclature, Definitions, and Evolution of the Kinetic Mechanism --;A. Nomenclature --;B. Evolution of Initial Rate Kinetics --;References --;II Derivation of Initial Velocity Rate Equations --;A. Definitions and Derivations --;B. The Equilibrium Assumption --;C. Derivation of Complex Steady-State Rate Equations --;D. Derivation of the Rate Equation Using the Rapid Equilibrium Assumption --;E. Derivation of Initial Rate Equations Using a Combination of Equilibrium and Steady-State Assumptions --;F. Derivation of Steady-State Rate Equations by Using the Digital Computer --;References --;III Experimental Protocol and Plotting of Kinetic Data --;A. General Considerations --;B. Analysis of Radioactive Substrates and Determination of Radiopurity --;C. pH Effects --;D. Substrate Concentration --;E. Studies of Forward and Reverse Reactions --;F. Studies of Nucleotide Dependent Enzymic Reactions --;G. The Kinetic Assay --;H. Plotting Methods --;I. Graphical Procedures --;J. The Point of Convergence of Sequential Double Reciprocal Plots as a Criterion of Kinetic Mechanism --;K. Protocol and Data Plotting for Three Substrate Systems --;L. Graphical Methods for Differentiating between Steady-State and Equilibrium Ordered Bi Bi Mechanisms --;References --;IV Use of Competitive Substrate Analogs and Alternative Substrates for Studying Kinetic Mechanisms --;A. Competitive Inhibition --;B. Partial Competitive Inhibition --;C. Noncompetitive Inhibition --;D. Ucompetitive Inhibition --;E. Nonlinear Enzyme Inhibition --;F. The Use of Substrate Analogs for Studying Kinetic Mechanisms --;G. Cleland's Rules for Dead End Inhibition --;H. The Stereochemical Nature of Enzyme and Substrate Interaction --;I. Kinetics of Enzyme Specificity --;J. The Kinetics of Transition State Analogs --;References --;V Product, Substrate, and Alternative Substrate Inhibition --;A. Product Inhibition Experiments --;B. Substrate Inhibition --;C. Alternative Substrate Inhibition --;D. Alternative Product Inhibition --;E. Multisite Ping Pong Mechanisms --;F. Enzymes with Identical Substrate-Product Pairs --;References --;VI Isotope Exchange --;A. Abortive Complex Formation --;B. Derivation of Rate Equations --;C. Substrate Synergism --;D. Calculation of Kinetic Parameters --;E. Experimental Protocol --;F. Isotope-Trapping --;References --;VII Isomerization Mechanisms and the? and Haldane Relationships --;A. The? Relationships --;B. The Haldane Relationships --;C. Isomerization Mechanisms --;References --;VIII The Effect of Temperature and pH on Enzyme Activity --;A. Effect of pH on Enzyme Kinetics --;B. The Effect of Temperature on Enzyme Catalyzed Reactions --;References --;IX Cooperativity and Allostery --;A. Cooperativity --;B. Molecular Models --;C. Kinetic Models --;D. Allostery --;E. Product Effects --;References --;Appendix I Rate Equations, Determinants, and Haldane Expressions for Some Common Kinetic Mechanisms --;Appendix II A Computer Program for Deriving Enzyme Rate Equations --;Appendix III Plotting and Statistical Analysis of Kinetic Data Using the OMNITAB Program.

متن يادداشت

Enzyme kinetics has undergone very rapid growth and development during the past fifteen years and has been well received by the biochemical community.

موضوع مستند نشده

Enzymes -- metabolism.

موضوع مستند نشده

Life sciences.

موضوع مستند نشده

Medicine.

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

by Herbert J. Fromm.

مستند نام اشخاص تاييد نشده

Herbert J Fromm

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y