عنوان

Parameters for pesticide QSAR and PBPK/PD models for human risk assessment /

شابک

0841226458 (alk. paper)

شابک

9780841226456 (alk. paper)

شماره

dltt

عنوان اصلي

Parameters for pesticide QSAR and PBPK/PD models for human risk assessment /

نام عام مواد

[Book]

نام نخستين پديدآور

James B. Knaak, editor, Charles Timchalk, editor, Rogelio Tornero-Velez, editor ; sponsored by the ACS Division of Agrochemicals

محل نشرو پخش و غیره

Washington, DC :

نام ناشر، پخش کننده و غيره

American Chemical Society,

تاریخ نشرو بخش و غیره

c2012

نام خاص و کميت اثر

xii, 349 p. :

ساير جزييات

ill., col. pl. ;

ابعاد

24 cm

عنوان فروست

ACS symposium series ;

مشخصه جلد

1099

متن يادداشت

Includes bibliographical references and indexes

متن يادداشت

Parameters for pesticide QSAR and PBPK/PD models to inform human risk assessments -- Chiral chemistry and toxicity assessments for pyrethroid pesticides -- Direct chiral separation of pyrethroid isomers by HPLC with chiral stationary phases -- Biotransformation and enzymes responsible for metabolism of pyrethroids in mammals -- Characterization of potential age-related differences in pyrethroid pharmacokinetics -- 15 factors of percutaneous penetration of pesticides -- Percutaneous absorption of pesticide formulations -- Human metabolic interactions of pesticides : inhibition, induction and activation -- Paraoxonase 1 (PON1) status in risk assessment for organophosphate exposure and pharmacokinetics -- Carboxylesterases : a multifunctional enzyme involved in pesticide and lipid metabolism -- Behavioral changes in adult and young rats as indications of cholinesterase inhibition -- Comparison of esterase sensitivity, metabolic efficiency, and toxicity levels of two organophosphorus insecticides, parathion and chlorpyrifos -- Regional brain dosimetry for the organophosphorus insecticide chlorpyrifos in the preweanling rat -- Pyrethroid actions on sodium channels : isoform and species specificity -- In vitro and in vivo experimental data for development and use of pharmacokinetic models for in vitro to in vivo extrapolation of pyrethroid insecticides -- In silico strategies for modeling stereoselective metabolism of pyrethroids -- Quantitative structure-activity relationships for organophosphate enzyme inhibition -- Computational approaches for developing informative prior distributions for bayesian calibration of PBPK models -- Use of cytochrome P450-specific parameters and human biomarker data to develop a human physiologically based pharmacokinetic/pharmacodynamic model for dermal chlorpyrifos exposure -- Use of in vitro data in PBPK models : an example of in vitro to in vivo extrapolation with carbaryl

بدون عنوان

0

موضوع مستند نشده

Chemical models, Congresses

موضوع مستند نشده

Pharmacokinetics, Congresses

موضوع مستند نشده

Risk assessment, Congresses

موضوع مستند نشده

Models, Chemical, Congresses

موضوع مستند نشده

Pesticides-- toxicity, Congresses

موضوع مستند نشده

Pharmacokinetics, Congresses

موضوع مستند نشده

Quantitative Structure-Activity Relationship, Congresses

موضوع مستند نشده

Risk Assessment, Congresses

شماره

ويراست

شماره رده

نشانه اثر

شماره رده

مستند نام اشخاص تاييد نشده

Knaak, James B

مستند نام اشخاص تاييد نشده

Timchalk, Charles

مستند نام اشخاص تاييد نشده

Tornero-Velez, Rogelio

مستند نام تنالگان تاييد نشده

American Chemical Society

مستند نام تنالگان تاييد نشده

American Chemical Society., Division of Agrochemicals

تاريخ عمليات

20130504000024.0

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y