عنوان

Case studies in modern drug discovery and development /

شابک

0470601817 (cloth)

شابک

9780470601815 (cloth)

شماره

dltt

عنوان اصلي

Case studies in modern drug discovery and development /

نام عام مواد

[Book]

نام نخستين پديدآور

edited by Xianhai Huang, Robert G. Aslanian

محل نشرو پخش و غیره

Hoboken, N.J. :

نام ناشر، پخش کننده و غيره

John Wiley & Sons,

تاریخ نشرو بخش و غیره

c2012

نام خاص و کميت اثر

xviii, 451 p., [8] p. of plates :

ساير جزييات

ill. (some col.) ;

ابعاد

26 cm

متن يادداشت

Includes bibliographical references and index

متن يادداشت

Introduction: drug discovery in difficult times / Malcom MacCoss -- Discovery and development of the DPP-4 inhibitor JANUVIA (Sita-gliptin) / Emma R. Parmee ... [et al.] -- Olmesartan medoxomil, an angiotensin II receptor blocker / Hiroaki Yanagisawa, Hiroyuki Koike, and Shini-chiro Miura -- Discovery of heterocyclic phosphonic acids as novel AMP mimics that are potent and selective fructose-1,6-bisphosphatase inhibitors and elicit potent glucose-lowering effects in diabetic animals and humans / Qun Dang and Mark D. Erion -- Setting the paradigm of targeted drugs for the treatment of cancer : Imatinib and Nilotinib, therapies for chronic myelogenous leukemia / Paul W. Manley and Jürg Zimmermann -- Amrubicin, a completely synthetic 9-aminoanthracycline for extensive-disease small-cell lung cancer / Mitsuharu Hanada -- The discovery of dual IGF-1R and IR inhibitor FQIT for the treatment of cancer / Meizhong Jin, Elizabeth Buck, and Mark J. Mulvihill -- Discovery and development of Montelukast (Singulair) / Robert N. Young -- Discovery and development of Maraviroc, a CCR5 antagonist for the treatment of HIV infection / Patrick Dorr, Blanda Stammen, Elna van der Ryst -- Discovery of antimalarial drug Artemisinin and beyond / Weiwei Mao, Yu Zhang, and Ao Zhang -- Discovery and process development of MK-4965, a potent nonnucleoside reverse transcriptase inhibitor / Yong-Li Zhong, Thomas J. Tucker, and Jingjun Yin -- Discovery of Boceprevir and Narlaprevir : the first and second generation of HCV NS3 protease inhibitors / Kevin X. Chen and F. George Njoroge -- The discovery of Samsca (Tolvaptan) : the first oral nonpeptide vasopressin receptor antagonist / Kazumi Kondo and Yoshitaka Yamamura -- SILODOSIN (Urief, Rapaflo, Thrupas, Urorec, Silodix) : a selective à1A adrenoceptor antagonist for the treatment of benign prostatic hyperplasia / Masaki Yoshida ... [et al.] -- Raloxifene : a selective estrogen receptor modulator (SERM) / Jeffrey A. Dodge and Henry U. Bryant

بدون عنوان

0

موضوع مستند نشده

Drug development, Case studies

موضوع مستند نشده

Drugs-- Design, Case studies

موضوع مستند نشده

Pharmaceutical chemistry, Case studies

موضوع مستند نشده

Drug Discovery

موضوع مستند نشده

Drug Evaluation

شماره

ويراست

شماره رده

شماره رده

مستند نام اشخاص تاييد نشده

Aslanian, Robert G

مستند نام اشخاص تاييد نشده

Huang, Xianhai

تاريخ عمليات

20120716123957.0

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y