عنوان

Peptidomimetics in organic and medicinal chemistry /

شابک

111868303X (electronic bk.)

شابک

1118683846 (electronic bk.)

شابک

9781118683033 (electronic bk.)

شابک

9781118683842 (electronic bk.)

شابک اشتباه

1118683145

شابک اشتباه

9781118683149

شابک اشتباه

9781119950608 (hardback)

شماره

dltt

عنوان اصلي

Peptidomimetics in organic and medicinal chemistry /

نام عام مواد

[Book]

نام نخستين پديدآور

Dr. Andrea Trabocchi and Professor Antonio Guarna

تاريخ

1404

نام خاص و کميت اثر

1 online resource

متن يادداشت

Includes bibliographical references and index

متن يادداشت

"A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or biological activity. It is a very powerful approach for the generation of small-molecule-based drugs as enzyme inhibitors or receptor ligands.Peptidomimetics in Organic and Medicinal Chemistry outlines the concepts and synthetic strategies underlying the building of bioactive compounds of a peptidomimetic nature. Topics covered include the chemistry of unnatural amino acids, peptide- and scaffold-based peptidomimetics, amino acid-side chain isosteres, backbone isosteres, dipeptide isosteres, beta-turn peptidomimetics, proline-mimetics as turn inducers, cyclic scaffolds, amino acid surrogates, and scaffolds for combinatorial chemistry of peptidomimetics. Case studies in the hit-to-lead process, such as the development of integrin ligands and thrombin inhibitors, illustrate the successful application of peptidomimetics in drug discovery"--

متن يادداشت

"Peptidomimetics in Organic and Medicinal Chemistry outlines the concepts and synthetic strategies underlying the building of bioactive compounds of a peptidomimetic nature"--

عنوان

Peptidomimetics in organic and medicinal chemistry

شماره استاندارد بين المللي کتاب و موسيقي

9781119950608

موضوع مستند نشده

Drugs-- Design.

موضوع مستند نشده

Peptide drugs.

موضوع مستند نشده

Proteins-- Therapeutic use.

موضوع مستند نشده

MED-- 071000

شماره

ويراست

شماره رده

مستند نام اشخاص تاييد نشده

Trabocchi, Andrea

مستند نام اشخاص تاييد نشده

Guarna, Antonio

مستند نام تنالگان تاييد نشده

Ohio Library and Information Network.

تاريخ عمليات

20140415154310.0

قواعد فهرست نويسي ( بخش توصيفي )

rda

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y