edited by Howard D. Lipshitz, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada
وضعیت ویراست
وضعيت ويراست
First edition
مشخصات ظاهری
نام خاص و کميت اثر
xiii, 415 pages, 18 unnumbered pages of color lates :
ساير جزييات
illustrations ;
ابعاد
24 cm
فروست
عنوان فروست
Current topics in developmental biology,
مشخصه جلد
volume 113
شاپا ي ISSN فروست
0070-2153 ;
یادداشتهای مربوط به کتابنامه ، واژه نامه و نمایه های داخل اثر
متن يادداشت
Includes bibliographical references and index
یادداشتهای مربوط به مندرجات
متن يادداشت
The maternal-to-zygotic transition in C. elegans / Scott Robertson and Rueyling Lin. Introduction ; Components of the MZT ; Major regulators/events that coordinate the MZT ; Concluding remarks -- Regulation and function of maternal gene products during the maternal-to-zygotic transition in Drosophila / John D. Laver [and others] ; Introduction ; Overview of oogenesis and early embryogenesis ; Maternal factors during oocyte maturation ; Maternal factors during egg activation and early embryogenesis ; The maternal-to-zygotic transition in primordial germ cells ; Conclusion and future prospects -- Transcriptional activation of the zygotic genome in Drosophila / Melissa M. Harrison and Michael B. Eisen. Introduction ; Activating transcription of the zygotic genome ; Mechanisms regulating transcriptional activation during the MZT ; Chromatin dynamics during the MZT ; The role of cis-Regulatory elements in regulating zygotic transcription ; Concluding remarks -- Coordinating cell cycle remodeling with transcriptional activation at the Drosophila MBT / Shelby A. Blythe and Eric F. Wieschaus. Introduction ; What happens at the MBT? ; Mechanisms for timing zygotic genome activation ; Concluding remarks -- Germ line versus soma in the transition from egg to embryo / S. Zachary Swartz and Gary M. Wessel. The big picture ; Are METs universal? ; General activation of the embryonic genome ; Activation of regionally specific gene regulatory networks ; Loss of cleavage synchrony : a cause of effect of embryonic control? ; Degradation of the maternally supplied transcription ; Separating the soma from the germ line : a critical fork in the road ; Different roads lead to a conserved germ line program ; PGC specification by induction ; PGC specification by preloading ; Evolutionary transition of PGC segregation in the echinoderms ; Putting your germ cells in the freezer : possible advantages for preloaded specification ; Are METs different between the germ line and soma? : transcriptional repression in PGCs ; Differential stability of mRNA in the germ line and soma ; NMETs are delayed in PGCs ; A continuum of maternal and embryonic contributions to development -- The maternal-to-zygotic transition during vertebrate development : a model for reprogramming / Valeria Yartseva and Antonio J. Giraldez. Introduction ; Mechanisms to maternal mRNA clearance during the MZT ; Consequences of failure of maternal mRNA clearance ; MZT connection to other transitions and reprogramming ; Concluding remarks -- Building the future : post-transcriptional regulation of cell fate decisions prior to the Xenopus midblastula transition / Michael D. Sheets. Introduction ; Regulation of maternal mRNAs in the Xenopus embryo ; miRNA regulation of mRNAs during early Xenopus development ; Translational control of mRNAs encoding cell fate determinants - Regulation of maternal proteins in the Xenopus embryo ; Regulated proteolysis and the control of maternal signaling pathways ; The Xenopus maternal proteome ; The maternal phosphoproteome ; Metabolism and metabolomics ; Conclusions -- The Xenopus maternal-to-zygotic transition from the perspective of the germline / Jing Yang [and others]. Introduction ; Germ-plasm RNAs and cytoskeletal dynamics : stage VI Oocyte ; Germ plasm and cytoskeletal dynamics : oocyte maturation/fertilization ; Maternal determinants for two lineages inherited by the same blastomeres : a dilemma ; Mechanisms for protecting the germline during the MZT ; PGCs are transcriptionally repressed at the MBT ; How does the germline escape the MBT? ; RNA degradation during the MZT ; Stability of germline RNAs and proteins ; The PGC late-gastrula transition -- Sculpting the transcriptome during the oocyte-to-embryo transition in mouse / Petr Svoboda [and others]. Introduction ; Overview of significant events during OET ; The OET : the mother of all transcriptome remodeling -- The maternal-to-zygotic transition in flowering plants : evidence, mechanisms, and plasticity / Celia Baroux and Ueli Grossniklaus. Seed development ; a largely maternal affair ; Emancipation of the plant embryo ; Progressive zygotic gene activation ; Mechanisms of zygotic genome activation ; The dynamics of the maternal-to-zygotic transition vary depending on plant species and genetic background ; Biological functions of the maternal-to-zygotic transition in plants ; Unresolved questions and outlook -- the maternal-to-zygotic transition in higher plants : available approaches, critical limitations, and technical requirements / Peng Zhao and Meng-Xiang Sun. Zygote development and embryogenesis in angiosperms ; The MZT during early angiosperm embryogenesis ; Studies on the MZT during embryogeneis and technical limitations ; Current techniques used to study the MZT in higher plants ; Conclusions and perspectives