INTERNATIONAL STANDARD BOOK NUMBER
(Number (ISBN
9789400745308
NATIONAL BIBLIOGRAPHY NUMBER
Country Code
IR
Number
EN-58823
LANGUAGE OF THE ITEM
.Language of Text, Soundtrack etc
انگلیسی
COUNTRY OF PUBLICATION OR PRODUCTlON
Country of publication
IR
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Site-Directed Insertion of Transgene
General Material Designation
[Book]
First Statement of Responsibility
/ [electronic resource
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
New York
Name of Publisher, Distributor, etc.
: Springer
Date of Publication, Distribution, etc.
, July 2012.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
xiii, 380 p., ill, 23.500 015.500 cm.
SERIES
Series Title
(Topics in Current Genetics series23)
NOTES PERTAINING TO PUBLICATION, DISTRIBUTION, ETC.
Text of Note
Electronic
CONTENTS NOTE
Text of Note
AnnotationThe post-genomic era has brought new challenges and opportunities in all fields of the biology. In this context, several genome engineering technologies have emerged that will help deciphering genes function by as well as improve gene therapy strategies. Genomic modifications such as knock-in, knock-out, knock-down, sequence replacement or modification can today be routinely performed. However, in front of this large palette of methodologies scientists may experience difficulties to gather useful informations scattered within the literature. This book aims to present the state of this field from basic mechanisms of site-directed modifications to their applications in a wide range of organisms such as bacteria, yeast, plants, insects, mammals. It will discuss the problems encountered when using the random integration strategy and present the recent advances made in targeted genome modification. Technologies based on Zinc Finger nucleases, Meganucleases, TALEN, CRE and FLP recombinase, C31 integrase, transposases and resolvases are fully detailed with their strengths and weaknesses. All these informations will help students and experienced researchers to understand and choose the best technology for their own purposes.
TOPICAL NAME USED AS SUBJECT
Genomics
Electronic books
LIBRARY OF CONGRESS CLASSIFICATION
Class number
E-BOOK
PERSONAL NAME - SECONDARY RESPONSIBILITY
Renault, SylvaineEditoredt
Duchateau, PhilippeEditoredt
ORIGINATING SOURCE
Country
ایران
ELECTRONIC LOCATION AND ACCESS
Host name
9789400745308.pdf
Access number
عادی
Compression information
عادی
Date and Hour of Consultation and Access
9789400745308.pdf
Electronic Format Type
متن
old catalog
e
BL
1
a
Y
