عنوان

Protein engineering and design

(Number (ISBN

9781420076585 (hardcover : alk. paper)

Country Code

IR

Number

E-8495

.Language of Text, Soundtrack etc

انگلیسی

Country of publication

IR

Title Proper

Protein engineering and design

General Material Designation

[Book]

First Statement of Responsibility

/ edited by Sheldon J. Park, Jennifer R. Cochran

Place of Publication, Distribution, etc.

Boca Raton

Name of Publisher, Distributor, etc.

: CRC Press,

Date of Publication, Distribution, etc.

, c2010.

Specific Material Designation and Extent of Item

xiv, 402 p., [16] p. of plates

Other Physical Details

: ill. (some col.)

Dimensions

; 25 cm.

Series Title

(London Mathematical Society student texts

Volume Designation

; 75.)

Text of Note

Print - Electronic

Text of Note

Includes bibliographical references and index.

Text of Note

"Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fields, Protein Engineering and Design aims to cultivate a synergistic approach to protein science. The first half of the book discusses experimental approaches to protein engineering and starts by describing several high-throughput screening platforms for protein engineering. Key techniques used for diversity generation are also discussed. The next few chapters present examples of therapeutics, enzymes, biomaterials, and other proteins that have been engineered by rational or combinatorial approaches. The section finishes with a chapter on the use of non-natural amino acids in protein engineering. The second half of the book introduces computational protein design, beginning with a chapter on computational and informatics algorithms used in protein engineering. Core components of computational protein design are then discussed in detail, and examples of heuristic protein design are provided. Subsequent chapters present examples of how computational design has played a critical role in advancing the field of protein engineering. Concluding with a chapter outlining current challenges in the field, this book makes computational protein design and diversity-oriented protein engineering widely accessible to a broad audience in academia and industry alike."--Publisher's description.

Text of Note

Phage display systems for protein engineering / Andreas Ernst and Sachdev S. Sidhu -- Cell surface display systems for protein engineering / Sarah J. Moore ... [et al.] -- Cell-free display systems for protein engineering / Pamela A. Barendt and Casim A. Sarkar -- Library construction for protein engineering / Daesa Lipovesek ... [et al.] -- Design and engineering of synthetic binding proteins using nonantibody scaffolds / Shohei Koide -- Combinatorial enzyme engineering / Patrick C. Cirino and Christopher S. Frei -- Engineering of therapeutic proteins / Fei Wen, Sheryl B. Rubin-Pitel, and Huimin Zhao -- Protein engineered biomaterials / Cheryl Wong Po Foo and Sarah C. Heilshorn -- Protein engineering using noncanonical amino acids / Deniz Yeuksel ... [et al.] -- Computer graphics, homology modeling, and bioinformatics / David F. Green -- Knowledge-based protein design / Michael A. Fisher ... [et al.] -- Molecular force fields / Patrice Koehl -- Rotamer libraries for molecular modeling and design of proteins / Hidetoshi Kono -- Search algorithms / Julia M. Shifman and Menachem Fromer -- Modulating protein structure / M.S. Hanes, T.M. Handel, and A.B. Chowdry -- Modulation of intrinsic properties by computational design / Vikas Nanda, Fei Xu, and Daniel Hsieh -- Modulating protein interactions by rational and computational design / Jonathan S. Marvin and Loren L. Looger -- Future challenges of computational protein design / Eun Jung Choi, Gurkan Guntas, and Brian Kuhlman.

Title

London Mathematical Society student texts

Volume Number

75

Protein engineering.

Protein Engineering.

Models, Molecular.

Proteins--chemistry

Number

Class number

Book number

Class number

Book Number

Park, Sheldon J

Cochran, Jennifer R

Country

ایران

Host name

Protein engineering and design/

Access number

عادی

Compression information

عادی

Electronic name

E-8495.pdf

Bits per second

0

Contact for access assistance

ایمانی

Electronic Format Type

متن

File size

0

Record control number

E-8495

Public note

انگلیسی

old catalog

pe

BL

1

a

Y