Approaches to the conformational analysis of biopharmaceuticals
General Material Designation
[Book]
First Statement of Responsibility
/ Roger L. Lundblad
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Boca Raton
Name of Publisher, Distributor, etc.
: CRC Press,
Date of Publication, Distribution, etc.
, c2010.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
xiii, 354 p.
Other Physical Details
: ill.
Dimensions
; 25 cm.
SERIES
Series Title
(Protein science series.)
NOTES PERTAINING TO PUBLICATION, DISTRIBUTION, ETC.
Text of Note
Print - Electronic
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index.
CONTENTS NOTE
Text of Note
Introduction to biopharmaceutical conformational analysis : issues and methods -- Comparability of biotechnological/biological products and biological generics -- Application of native electrophoresis for the study of protein conformation -- Affinity chromatography including hydrophobic interaction chromatography in the study of biopolymer conformation -- Size-exclusion chromatography and bimolecular conformation -- Use of analytical ultracentrifugation to study biomolecular conformation -- Use of differential scanning calorimetry to measure conformational change in proteins and other biomacromolecules -- Light scattering and biomacromolecular conformation -- Use of luminescence to measure conformational change in biopharmaceuticals with emphasis on protein and protein drug products -- Near-infrared spectroscopy and macromolecular conformation -- Use of mid-infrared and Fourier transform infrared spectroscopy to study conformation of biomacromolecules -- Use of Raman spectroscopy to evaluate biopharmaceutical conformation -- The use of UV-VIS spectrophotometry for the characterization of biopharmaceutical products -- Use of optical rotatory dispersion and circular dichroism to study therapeutic biomacromolecule conformation -- Use of nuclear magnetic resonance for the characterization of biotherapeutic products -- Use of chemical probes for the study of protein conformation -- Use of hydrogen exchange in the study of biopharmaceutical conformation -- Use of chemical modification for the conformational analysis of biopharmaceuticals -- Use of immunology to characterize biopharmaceutical conformation -- Use of limited proteolysis to study the conformation of proteins of biotechnological interest -- Other technologies for the characterization of conformational change in biopharmaceuticals -- Development of an experimental approach for the study of the conformation of a biological therapeutic product.
SERIES
Title
Protein science series
TOPICAL NAME USED AS SUBJECT
Protein drugs--Conformation
Pharmaceutical biotechnology.
Biopharmaceutics--methods
Protein Conformation.
Proteins--analysis
DEWEY DECIMAL CLASSIFICATION
Number
615
.
7
LIBRARY OF CONGRESS CLASSIFICATION
Class number
RS431
Book number
.
P75
,
L86
2010
OTHER CLASS NUMBERS
Class number
QV
38
Book Number
L962a
2010
PERSONAL NAME - PRIMARY RESPONSIBILITY
Lundblad, Roger L
ORIGINATING SOURCE
Country
ایران
ELECTRONIC LOCATION AND ACCESS
Host name
Approaches to the conformational analysis of biopharmaceuticals