عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
NATIONAL BIBLIOGRAPHY NUMBER
Number
TL51664
LANGUAGE OF THE ITEM
.Language of Text, Soundtrack etc
انگلیسی
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Synthesis of Folate-appended β-Cyclodextrin Using Phenanthroline as Linker for Cancer Targeting Drug Delivery
General Material Designation
[Thesis]
First Statement of Responsibility
Russel, Nadim Shahriar
Subsequent Statement of Responsibility
Karim, Mohammad
.PUBLICATION, DISTRIBUTION, ETC
Name of Publisher, Distributor, etc.
Tennessee State University
Date of Publication, Distribution, etc.
2019
GENERAL NOTES
Text of Note
88 p.
DISSERTATION (THESIS) NOTE
Dissertation or thesis details and type of degree
M.S.
Body granting the degree
Tennessee State University
Text preceding or following the note
2019
SUMMARY OR ABSTRACT
Text of Note
I have synthesized cancer targeting drug delivery system that contains β-cyclodextrin as a drug carrier and folic acid as a targeting ligand. Folic acid was selected as a cancer targeting ligand because folic acid receptor are highly expressed in a variety of tumor types. β-cyclodextrin and folic acid were connected through a linker [1,10-phenanthroline or 5-(hydroxymethyl) furfural]. β-cyclodextrin and folic acid were attached to the linker by formation of Schiff base and ester, respectively. Our targeted synthetic products were confirmed by NMR, Mass and IR spectroscopy. We anticipate that our synthetic products can confer cancer cell-specific drug delivery as well as desired properties such as nanoparticle formation.
UNCONTROLLED SUBJECT TERMS
Subject Term
Chemistry
PERSONAL NAME - PRIMARY RESPONSIBILITY
Russel, Nadim Shahriar
PERSONAL NAME - SECONDARY RESPONSIBILITY
Karim, Mohammad
CORPORATE BODY NAME - SECONDARY RESPONSIBILITY
Tennessee State University
ELECTRONIC LOCATION AND ACCESS
Electronic name
مطالعه متن کتاب p
[Thesis]
276903
a
Y
