عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
NATIONAL BIBLIOGRAPHY NUMBER
Number
TL50826
LANGUAGE OF THE ITEM
.Language of Text, Soundtrack etc
انگلیسی
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Demographics and Quality of Life Effects of Normobaric Oxygen on Cohort of Patients with Retinal Vein Occlusions
General Material Designation
[Thesis]
First Statement of Responsibility
Minturn, Robert J.
Subsequent Statement of Responsibility
Arroyo, Jorge
.PUBLICATION, DISTRIBUTION, ETC
Name of Publisher, Distributor, etc.
Boston University
Date of Publication, Distribution, etc.
2019
GENERAL NOTES
Text of Note
56 p.
DISSERTATION (THESIS) NOTE
Dissertation or thesis details and type of degree
M.S.
Body granting the degree
Boston University
Text preceding or following the note
2019
SUMMARY OR ABSTRACT
Text of Note
Purpose: This study examined the effects of normobaric oxygen in patients diagnosed with either a Central Retinal Vein Occlusion (CRVO) or Branched Retinal Vein Occlusion (BRVO) who had previously undergone treatment via Anti-VEGF or PRP treatment. The investigation looked into the changes in Macular Thickness (MT) and Visual Acuity (VA). Methods: This pilot study analyzed patient data from Beth Israel Deaconess Medical Center (Boston, MA) that had been diagnosed with Retinal Vein Occlusions. The patients were brought in and given 3 hours of normobaric oxygen via an oxygen concentrator with imaging and vision checked both before and after the therapy. Results: Eighty-eight percent of our patients in this pilot study saw a decrease in macular thickness after 3-hour oxygen therapy. The mean change in Maximal Macular Thickness was a decrease of 7.1% which was statistically significant when compared to healthy eyes (p<0.001). Additionally, 44% of patients saw an increase in visual acuity, the primary measure of vision. Visual acuity showed a statistically significant change when compared to changes in healthy eyes (p=0.015). No statistical significance was found in the testing of contrast sensitivity nor intraocular pressure. Conclusion: Our study showed improvement in central macular thickness and quality of life for individuals using noninvasive normobaric hyperoxia as a treatment for retinal vein occlusions. However, further research is needed to improve the impact of the study and a full randomized control trial should be implemented to further understand the potential impacts of a noninvasive normobaric hyperoxia treatment as a means to alleviate symptoms in retinal vein occlusions. In addition, in the future oxygen supplementation in conjunction with periodic injections of Anti-VEGF could be investigated as a treatment regimen with potential benefits beyond individual therapy.
UNCONTROLLED SUBJECT TERMS
Subject Term
Biochemistry
Subject Term
Medicine
Subject Term
Ophthalmology
Subject Term
Physiology
Subject Term
Public health
PERSONAL NAME - PRIMARY RESPONSIBILITY
Minturn, Robert J.
PERSONAL NAME - SECONDARY RESPONSIBILITY
Arroyo, Jorge
CORPORATE BODY NAME - SECONDARY RESPONSIBILITY
Boston University
ELECTRONIC LOCATION AND ACCESS
Electronic name
مطالعه متن کتاب p
[Thesis]
276903
a
Y
