عنوان

In vitro methods in pharmaceutical research /

(Number (ISBN

0080534600

(Number (ISBN

012163390X

(Number (ISBN

1281466816

(Number (ISBN

9780080534602

(Number (ISBN

9780121633905

(Number (ISBN

9781281466815

Number

b788141

Title Proper

In vitro methods in pharmaceutical research /

General Material Designation

[Book]

First Statement of Responsibility

edited by José V. Castell and María José Gómez-Lechón.

Place of Publication, Distribution, etc.

San Diego :

Name of Publisher, Distributor, etc.

Academic Press,

Date of Publication, Distribution, etc.

©1997.

Specific Material Designation and Extent of Item

1 online resource (ix, 467 pages) :

Other Physical Details

illustrations

Text of Note

Includes bibliographical references and index.

Text of Note

D.W. Straughan, J.H. Fentem, and M. Balls, Replacement Alternative and Complementary In Vitro Methods in Pharamaceutical Research. -- M.D. Barratt and M. Chamberlain, Integration of QSAR and In Vitro Toxicology. -- F.A. Barile, Continuous Cell Lines as a Model for Drug Toxicity Assessment. -- P. Bach, In Vitro Models for Nephrotoxicity Studies. -- A.E.M. Vickers, Experimental In Vitro Models to Evaluate Hepatotoxicity. -- M.J. Gomez-Lechon, T. Donato, X. Ponsoda, R. Fabra, R. Trullenque, and J.V. Castell, Isolation, Culture and Use of Human Hepatocytes in Drug Research. -- E. McFarlane-Abdulla, and I.C. Campbell, Studies of Nephrotoxicity in Cellular Studies. -- M. Adolphe, S. Thenet-Gauci, and S. Demignot, Chondrocyte Culture: A Target System to Evaluate Pharmaco-Toxicological Effects of Drugs. -- E. Chacon, D. Acosta, and J.J. Lemasters, Primary Cultures of Cardiac Myocytes as In Vitro Models for Pharmacological andToxicological Assessments. -- R. Roguet, Cutaneous Pharmacotoxicology In Vitro. -- H. Spielmann, Ocular Irritation. -- M.A. Miranda, Phototoxicity of Drugs. -- I. de G. Mitchell and R.D. Combes, In Vitro Genotoxicity and Cell Transformation Assessment. -- B. Schmid, R. Bechter, and P. Kucera, The Use of Whole Embryo Cultures in In Vitro Teratogenicity Testing. -- J.V. Castell, M.J. Gomez-Lechon, X. Ponsoda, and R. Bort, In Vitro Investigation of the Molecular Mechanisms of Hepatotoxicity. -- A. Guillouzo, Biotransformation of Drugs by Hepatocytes. -- K. Mace, E.A. Offord, and A.M.A. Pfeifer, Drug Metabolism and Carcinogen Activation Studies with Human Genetically Engineered Cells.

0

Text of Note

In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are provided, along with a comparison of different techniques available. It is a welcome addition to the literature at a time when interest is growing in cellular in vitro models for toxicology and pharmacology studies. Key Features * Meets the continuing demand for information in this field * Compares In Vitro techniques with other methods * Describes cell-culture methods used to investigate toxicity in cells derived from different organs * Includes contributions by leading experts in the field.

Source for Acquisition/Subscription Address

Elsevier Science & Technology

Stock Number

81758:81758

Title

In vitro methods in pharmaceutical research.

International Standard Book Number

9780121633905

Drugs-- Research.

Pharmacy-- Research.

Cells, Cultured-- drug effects.

Drug-Related Side Effects and Adverse Reactions.

Toxicity Tests.

Drugs-- Research.

Farmacie.

In-vitro-onderzoek.

MEDICAL-- Pharmacology.

Pharmacy-- Research.

MED-- 071000

MMGT

Number

Edition

Class number

Book number

Class number

Class number

Book Number

Castell, José V.

Gómez-Lechón, María José.

Date of Transaction

20201207014547.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y