Introduction to retrovirus replication and retroviral vectors / Gary L. Buchschacher, Jr. -- HIV-1 replication / Eric O. Freed -- Determinants for lentiviral infection of non-dividing cells / Marie A. Vodicka -- HIV-1 vector systems / Narasimhachar Srinivasakumar -- HIV-2 and SIV vector systems / James R. Gilbert and Flossie Wong-Staal -- FIV vector systems / Sybille L. Sauter and Mehdi Gasmi -- EIAV, CAEV and other lentiviral vector systems / John C. Olsen -- Safety considerations in vector development / John C. Kappes and Xiaoyun Wu -- Prospects for gene therapy using HIV-based vectors / Jiing-Kuan Yee and John Zaia -- Ethical considerations in the use of lentiviral vectors for genetic transfer / Ina Roy.