Includes bibliographical references at chapter ends, and index.
SUMMARY OR ABSTRACT
Text of Note
The tiny microRNAs (miRNAs) can have huge impacts on the regulation of a variety of genes and play crucial roles in the fundamental cellular processes. Recent miRNA studies change the landscape of cancer genetics by scrutinizing the alterations of genome-wide miRNA expressions in most common cancers and their regulatory functions during the development of cancer. The connections between miRNAs and cancer are widespread enough to warrant more comprehensive investigations in the systems biology perspective. In "MicroRNA and Cancer: Methods and Protocols," internationally renowned experts provide the latest miRNA knowledge, the various techniques and methodologies currently available for cancer research application. Authoritative and cutting-edge, this volume serves researchers with the basic principles of experimental and computational methods for microRNA study in cancer research and provides a firm grounding for those who wish to further develop their own applications and tailor them to their own specific research needs.