عنوان

Liver regeneration and carcinogenesis :

(Number (ISBN

0080535542

(Number (ISBN

0123853559

(Number (ISBN

9780080535548

(Number (ISBN

9780123853554

Number

b755413

Title Proper

Liver regeneration and carcinogenesis :

General Material Designation

[Book]

Other Title Information

molecular and cellular mechanisms /

First Statement of Responsibility

edited by Randy L. Jirtle.

Place of Publication, Distribution, etc.

San Diego :

Name of Publisher, Distributor, etc.

Academic Press,

Date of Publication, Distribution, etc.

©1995.

Specific Material Designation and Extent of Item

1 online resource (xxiii, 402 pages) :

Other Physical Details

illustrations

Text of Note

Includes bibliographical references and index.

Text of Note

Liver Regeneration, Then and Now. Hepatocyte Growth Factor (HGF) and Its Receptor (MET) in Liver Regeneration, Neoplasia, And Disease. Structure and Functions of the HGF Receptor (C-Met). Expression and Function of Growth-Induced Genes During Liver Regeneration. Stem Cells and Hepatocarcinogenesis. Contributions of Hepadnavirus Research to Our Understanding of Hepatocarcinogenesis. Apoptosis and Hepatocarcinogenesis. Liver Tumor Promotion and the Suppression of P53-Dependant Cell Cycle Checkpoint Function. Mechanisms of Liver Tumor Promotion. Hypomethylation of DNA: A Epigenetic Mechanism that Can Facilitate the Aberrant Oncogene Expression Involved in Liver Carcinogenesis. Transgene-Based Strategies for Studying Liver Growth, Development and Cancer. Subject Index.

0

Text of Note

Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis, and liver tumor therapy. The contributors are pioneers and leaders in this field. * Logical organization of material in three detailed and comprehensive sections: liver regeneration, liver carcinogenesis, and liver tumor treatment * Contributors are pioneers and leaders in the field * There are currently no books on this subject on the market * Research focus is at the molecular level.

Text of Note

Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.

Source for Acquisition/Subscription Address

Elsevier Science & Technology

Stock Number

88515:88515

Title

Liver regeneration and carcinogenesis.

International Standard Book Number

9780123853554

Liver-- Cancer.

Liver-- Molecular aspects.

Liver-- Regeneration.

Pathology, Molecular.

Liver Neoplasms-- genetics.

Liver Regeneration.

Liver-- Cancer.

Liver-- Regeneration.

MEDICAL-- Hepatology.

Pathology, Molecular.

MED-- 114000

Number

Edition

Class number

Book number

Class number

Class number

Class number

Class number

Book Number

System Code

System Code

Jirtle, Randy L.

Date of Transaction

20201204153306.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y