عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
NATIONAL BIBLIOGRAPHY NUMBER
Number
TLets545434
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Secondary metabolites from Xylaria endophytes :
General Material Designation
[Thesis]
First Statement of Responsibility
Al-Busaidi, Harith
Title Proper by Another Author
the isolation and structure elucidation of secondary metabolites from Xylaria endophytes by chemical and spectroscopic methods
Subsequent Statement of Responsibility
Maitland, Derek J.
.PUBLICATION, DISTRIBUTION, ETC
Name of Publisher, Distributor, etc.
University of Bradford
Date of Publication, Distribution, etc.
2011
DISSERTATION (THESIS) NOTE
Dissertation or thesis details and type of degree
Thesis (Ph.D.)
Text preceding or following the note
2011
SUMMARY OR ABSTRACT
Text of Note
This thesis describes the isolation and structure elucidation of secondary metabolites from a number of endophytic Xylaria fungi. Six Xylaria endophytes were surface cultured on an aqueous malt extract-glucose medium. The fungus A311R, from a palm tree in Thailand, produced nonane-1,2,3-tricarboxylic acid, which was isolated for the first time as a natural product. Also isolated from the same fungus was spiculisporic acid; the first instance of isolation from a Xylaria fungus. The fungus 6RD12 produced cycloepoxydon, which was isolated for the first time from a Xylaria fungus, and 4,5,6-trihydroxy-3-propyl-3,4,6,7-tetrahydro-l//-isochromen- 8(5//)-one, which is a novel compound. The fungi A217R and A517R produced cytochalasin D, (S)-mellein and (3S,4S)-4-hydroxymellein as main secondary metabolites suggesting that the two fungi are the same species. The fungus X04 (Xylaria cf. juruensis) produced 2-Hydroxy-5-ethoxy-3-methylcyclohexa-2,5-dien- 1,4-dione as a novel compound, coriloxin as the main secondary metabolite in addition to (R)-mellein and a mixture of two stereoisomers of the 4-Hydroxymellein. The fungus 6RD8 produced (S)-Omethylmellein as the main secondary metabolite.
TOPICAL NAME USED AS SUBJECT
Endophyte ; Fungi ; NMR ; Secondary metabolites ; Structure elucidation ; Xylaria
PERSONAL NAME - PRIMARY RESPONSIBILITY
Al-Busaidi, Harith
PERSONAL NAME - SECONDARY RESPONSIBILITY
Maitland, Derek J.
CORPORATE BODY NAME - SECONDARY RESPONSIBILITY
University of Bradford
ELECTRONIC LOCATION AND ACCESS
Electronic name
مطالعه متن کتاب p
[Thesis]
276903
a
Y
