عنوان

Drugs Looking for Diseases :

(Number (ISBN

940113796X

(Number (ISBN

9789401137966

Number

b595853

Title Proper

Drugs Looking for Diseases :

General Material Designation

[Book]

Other Title Information

Innovative Drug Research and the Development of the Beta Blockers and the Calcium Antagonists

First Statement of Responsibility

by Rein Vos.

Place of Publication, Distribution, etc.

Dordrecht Springer Netherlands

Date of Publication, Distribution, etc.

1991

Specific Material Designation and Extent of Item

(XXX, 381 p).

Series Title

Developments in Cardiovascular Medicine, 120

Text of Note

We all know how much time, effort and money it takes to develop a new drug. Hundreds of chemical compounds have to be synthesized and thousands of different activities in biology, physiology, pharmacology, clinical investigation, management and marketing have to be initiated and coordinated. Each new drug starts a voyage of discovery through an unmapped terrain which is shrouded in mist and beset by pitfalls, as Dr. Rein Vos puts it in his absorbing inside story of the development of the beta-adrenoceptor blocking agents and the calcium antagonists. Indeed we know, for example, how long it took before the theory of Ahlquist of the alpha and beta adrenergic receptors was widely accepted. Similarly, it suffices to memorize shortly the difficulty of expanding the new concept of calcium antagonism through the national German boundaries into the world. This shows how laborious and complex pharmaceutical progress is, and we all will benefit from a deeper understanding of the process of innovative drug research.

Cardiology.

Philosophy of Medicine.

Class number

Book number

by Rein Vos.

Rein Vos

Electronic name

[Book]

Y