عنوان

Azapropazone :

(Number (ISBN

9400907133

(Number (ISBN

9401068062

(Number (ISBN

9789400907133

(Number (ISBN

9789401068062

Number

b592448

Title Proper

Azapropazone :

General Material Designation

[Book]

Other Title Information

20 years of clinical use

First Statement of Responsibility

edited by K.D. Rainsford.

Place of Publication, Distribution, etc.

Dordrecht

Name of Publisher, Distributor, etc.

Springer Netherlands

Date of Publication, Distribution, etc.

1990

Specific Material Designation and Extent of Item

(256 pages)

Text of Note

Section I Experimental.- 1 Introduction to therapy with azapropazone.- 2 The chemical classification of azapropazone.- 3 Survey of toxicological investigations of azapropazone.- 4 The mode of action of azapropazone in relation to its therapeutic actions in rheumatic conditions and its major side-effects.- 5 Pharmacokinetic properties of azapropazone in comparison to other NSAIDs.- 6 The pharmacokinetics of azapropazone.- 7 Mathematical model for assessing risk of gastrointestinal reactions to NSAIDs.- 8 Reduction of irreversible injury in animal models of myocardial ischaemia by treatment with azapropazone.- 9 Dual inhibitory effects of azapropazone on both neutrophil migration and function: relation to cardiovascular function.- 10 Aspects of clinical pharmacology and bioavailability of azapropazone.- 11 Immunochemical studies on azapropazone.- Section II Therapeutic Actions.- 12 Untersuchungen zur Arthrose [Studies in osteoarthritis].- 13 Studies on gout and urate elimination by azapropazone.- 14 Die Analgetische Wirksamkeit von Azapropazon [Analgesic effects of azapropazone].- 15 UEberblick uber die Anwendung von Azapropazon nach operativen Eingriffen und bei traumatisierten Patienten [Review of application of azapropazone in post-operative and traumatic conditions].- 16 Clinical trial methodology in rheumatoid arthritis: azapropazone studies.- 17 Comparative effects of azapropazone on the progression of joint pathology on osteoarthritis.- 18 Serious gastrointestinal reactions to azapropazone: an estimate of the risk.- 19 Tolerance of azapropazone: allergic and pseudo-allergic reactions and comparison with other NSAIDs.- 20 Haematological reactions.- 21 Epilogue, with some thoughts for research on azapropazone.

Internal medicine.

Medicine.

Toxicology.

Class number

Book number

edited by K.D. Rainsford.

K D Rainsford

Electronic name

[Book]

Y