Cover; Foreword; Contents; List of Abbreviations; Chapter 1: Introduction to Masked Mycotoxins; 1.1 Mycotoxins; 1.2 Masked Mycotoxins; 1.2.1 Terminology; 1.2.2 Historical Perspective; 1.2.3 Recent Developments; 1.2.4 Toxicity of Masked Mycotoxins; 1.3 Conclusion; References; Chapter 2: Natural Occurrence of Masked Mycotoxins; 2.1 Introduction; 2.2 Masked forms of DON; 2.2.1 Occurrence; 2.2.2 Ratios of DON-3-Glc to DON; 2.2.3 Occurrence in Beer; 2.2.4 Other DON Metabolites; 2.3 Masked Zearalenone; 2.4 Masked Fumonisins; 2.5 Ochratoxin A; 2.6 T2 and HT2 Toxins; 2.7 Fusarenon-X. 2.8 Other Masked Mycotoxins2.9 Effect of Climate on Occurrence; 2.10 Conclusion; References; Chapter 3: Immunologically-based Methods for Detecting Masked Mycotoxins; 3.1 Introduction; 3.1.1 Terminology; 3.1.2 Why use Immunoassays to Detect Masked Forms?; 3.1.3 CR of Immunoassays; 3.2 Immunoassays for Detecting Masked Mycotoxins; 3.2.1 Assays Developed for Parent Mycotoxins that Cross-react with Masked Forms; 3.2.2 Assays Developed Specifically for the Masked Forms; 3.3 Conclusion; Disclaimer; Acknowledgments; References. Chapter 4: Untargeted Analysis of Modified Mycotoxins using High-resolution Mass Spectrometry4.1 Analysis of Modified Mycotoxins by Traditional Liquid Chromatography-tandem Mass Spectrometry Methods; 4.2 Analysis of Modified Mycotoxins and Possibilities of High-resolution Mass Spectrometry; 4.3 Untargeted Analysis of Modified Fusarium Mycotoxins in Natural Products; 4.3.1 Fusarium Mycotoxins: Trichothecenes; 4.3.2 Fusarium Mycotoxins: Myco-estrogens; 4.4 Untargeted Analysis of Modified Mycotoxins in Human Biological Fluids; 4.4.1 Fusarium Mycotoxins; 4.5 Conclusion; References. Chapter 5: Transformation of Mycotoxins upon Food Processing: Masking, Binding and Degradation Phenomena5.1 Pre-milling; 5.2 Milling; 5.3 Extrusion; 5.4 Frying; 5.5 Baking; 5.6 Pasta Manufacturing; 5.7 Tortilla Manufacturing; 5.8 Beer Production; 5.9 Conclusion; References; Chapter 6: In Vitro Assays to Estimate the Toxicological Effects of Masked Mycotoxins; 6.1 Introduction; 6.2 Modern Mycotoxicology: Masked Mycotoxins; 6.2.1 Adverse Effects of Mycotoxins; 6.2.2 'Masking' of Mycotoxins: Toxicological Repercussions; 6.3 Toxicity Testing In Vitro; 6.3.1 Extrapolation to Human Toxicology. 6.3.2 Cytotoxicity of Masked Mycotoxins6.4 Bioaccessibility and Bioavailability Assessment In Vitro; 6.4.1 Human Digestion Models; 6.4.2 Caco-2 Permeability Assay; 6.5 Future Perspectives; 6.6 Conclusion; References; Chapter 7: Animal Models for Masked Mycotoxin Studies; 7.1 Introduction; 7.2 Animal Studies on Masked ZEN; 7.3 Animal Studies on Masked DON; 7.3.1 Stability of DON-3-Glc During Digestion; 7.3.2 Biological Activity of DON-3-Glc; 7.4 Animal Studies on Masked Fumonisins; 7.5 Conclusion; References; Chapter 8: Detoxification Strategies for Mycotoxins in Plant Breeding.
SUMMARY OR ABSTRACT
Text of Note
The first book to cover this fast developing field, Masked Mycotoxins in Food will provide a full overview of the issues relating to the toxicology of masked mycotoxins present in food products.