عنوان

Molecular Aspects of Myeloid Stem Cell Development

(Number (ISBN

3540604146

(Number (ISBN

3642852327

(Number (ISBN

9783540604143

(Number (ISBN

9783642852329

Number

b574661

Title Proper

Molecular Aspects of Myeloid Stem Cell Development

General Material Designation

[Book]

First Statement of Responsibility

edited by Linda Wolff, Archibald S. Perkins.

Place of Publication, Distribution, etc.

Berlin, Heidelberg

Name of Publisher, Distributor, etc.

Springer Berlin Heidelberg

Date of Publication, Distribution, etc.

1996

Specific Material Designation and Extent of Item

(xiv, 298 pages 98 illustrations, 2 illustrations in color.)

Series Title

Current topics in microbiology and immunology, 211.

Text of Note

Regulation of Myeloid Differentiation, Growth Arrest and Apoptosis --; Molecular Control of Development in Normal and Leukemic Myeloid Cells by Cytokines, Tumor Suppressor and Oncogenes --; Retinoic Acid Receptors in Hematopoiesis --; Role of c-myc in Myeloid Differentiation, Growth Arrest and Apoptosis --; Self Renewal and Differentiation in Primary Avian Hematopoietic Cells: An Alternative to Mammalian in Vitro Models? --; Receptors and Signal Transduction --; The Effect of C-raf Antisense Oligonucleotides on Growth Factor-Induced Proliferation of Hematopoietic Cells --; Protein Kinase C-?, an Important Signaling Molecule in the Platelet-Derived Growth Factor? Receptor Pathway --; Novel Adapter Proteins that Link the Human GM-CSF Receptor to the Phosphatidylinositol 3-Kinase and Shc/Grb2/ras Signaling Pathways --; Myb: Proliferation and Maintenance of Stage Specific Genes --; Functional Analysis of the c-myb Proto-Oncogene --; Structure and Function of the Proteins Encoded by the myb Gene Family --; The c-Myb Negative Regulatory Domain --; Myeloid-Specific Transcription --; Terminal Myeloid Gene Expression and Differentiation Requires the Transcription Factor PU. 1 --; A Role for STAT Family Transcription Factors in Myeloid Differentiation --; Regulation of C/EBP?/NF-M Activity by Kinase Oncogenes --; Function of PU. 1 (Spi-1), C/EBP, and AML1 in Early Myelopoiesis: Regulation of Multiple Myeloid CFS Receptor Promoters --; Regulation of Immature Myeloid Cell Differentiation by PEBP2/CBF, MYB, C/EBP and ETS Family Members --; Hematopoietic Transcriptional Regulation by the Myeloid Zinc Finger Gene, MZF-1 --; Coordinate Regulation of Neutrophil Secondary Granule Protein Gene Expression --; lnterleukin-5 Receptor? Subunit Gene Regulation in Human Eosinophil Development: Identification of a Unique Cis-Element that acts lie an Enhacer in Regulating Activity of the IL-5R? Promoter --; Molecular Aspects of Myeloid Leukemia. I. Murine Studies --; Retroviral Insertional Mutagenesis in Murine Promonocytic Leukemias:c-myband Mm/1. --; Molecular Analysis and Characterization of Two Myeloid Leukemia Inducing Murine Retroviruses --; Molecular Analysis of Evil, a Zinc Finger Oncogene Involved in Myeloid Leukemia --; Activation of Stat-related DNA-binding Factors by Erythropoietin and the Spleen Focus-Forming Virus --; The Neurofibromatosis Type 1 (NF1) Tumor Suppressor Gene and Myeloid Leukemia --; Molecular Aspects of Myeloid Leukemia. II. Human Studies --; Rearrangement of the AML1/CBFA2 Gene in Myeloid Leukemia with the 3; 21 Translocation:Expression of Co-Existing Multiple Chimeric Genes with Similar Functions as Transcriptional Repressors, but with Opposite Tumorigenic Properties --; Transcriptional Regulation by the t(8; 21)Fusion Protein, AML-1/ETO --; The Mixed Lineage Leukemia (MLL) Protein Involved in 11 q23 Translocations Contains a Domain that Binds Cruciform DNA and Scaffold Attachment Region (SAR) DNA --; Pathogenetic Role of the PML/RAR? Fusion Protein in Acute Promyelocytic Leukemia --; Involvement of the TEL Gene in Hematologic Malignancy by Diverse Molecular Genetic Mechanisms --; Transforming Properties of the Leukemic Inv(16) Fusion Gene CBFB-MYH11.

Text of Note

This volume publishes advances in the molecular regulation of myelopoiesis, depicting current ideas about the way cells progress from progenitors in the bone marrow and spleen to mature erythroid cells, macrophages, and neutrophilic granulocytes. In particular, emphasis is on signal transduction and transcriptional regulation of genes encoding growth factor receptors, functional macrophage and promyelocyte proteins, as well as molecules that control proliferation. A main feature of the volume is the examination of abnormal regulation of myelopoiesis as seen in leukemias and acute myelogenous leukemias (AML) in man. Since it is an overview of a recent workshop, this publication presents some of the newest and most exciting information in the field.

Cytology.

Immunology.

Medicine.

Class number

Book number

edited by Linda Wolff, Archibald S. Perkins.

A S Perkins

L Wolff

Electronic name

[Book]

Y