عنوان

Nucleic Acids and Molecular Biology

(Number (ISBN

3540508082

(Number (ISBN

3642837093

(Number (ISBN

9783540508083

(Number (ISBN

9783642837098

Number

b574453

Title Proper

Nucleic Acids and Molecular Biology

General Material Designation

[Book]

First Statement of Responsibility

edited by Fritz Eckstein, David M.J. Lilley.

Place of Publication, Distribution, etc.

Berlin, Heidelberg

Name of Publisher, Distributor, etc.

Springer Berlin Heidelberg

Date of Publication, Distribution, etc.

1989

Specific Material Designation and Extent of Item

(xi, 272 pages 70 illustrations, 5 illustrations in color.)

Series Title

Nucleic acids and molecular biology, 3.

Text of Note

Structural Studies of DNA Through Cleavage by the Hydroxyl Radical --; DNase Activity of 1,10-Phenanthroline-Copper Ion --; Structure of E. coli DNA Polymerase I, Large Fragment, and Its Functional Implications --; Resolution of Model Holliday Junctions in Vitro --; Structure and Mechanism of the trp Repressor/Operator System --; The deoR Repressor from E. coli and Its Action in Regulation-at-a-Distance --; Complexities in Gene Regulation by Promoter Methylation --; Transcriptional Regulation of Proto-Oncogene c-fos --; The Structural and Functional Domain Organization of the Chicken Lysozyme Gene Locus --; Mammalian Ribosomal Gene Transcription --; The Chemical Synthesis of Oligo- and Poly-ribonucleotides --; RNA Structure --; Pre-mRNA Splicing in Yeast --; Trans-Splicing of RNA --; Structure and Function of Bacterial RNase P --; Transposition in Plants --; Transgenic Plants and the Study of Plant Development.

Text of Note

A wide range of topics are covered, including articles on nucleic acid structure, through their interactions with proteins to the control of gene expression. A number of authors address the subject of RNA, including the difficult but important subject of its chemical synthesis, the complexities of its structures and the mechanisms of transcript splicing. The probing of DNA structure is reviewed in papers on the application of hydroxyl radical and 1,10 phenanthroline copper cleavages. A number of important DNA-protein interactions are discussed, including DNA polymerase, the tryptophan and deoR repressors, and the resolvase enzymes which cleave Holliday junctions in recombination. Gene transcription is also covered, from the points of view of DNA methylation, mammalian ribosomal and avian lysozyme genes, and the control of transcription in the proto-oncogene c-fos. Finally, the plant kingdom has not been forgotten with articles on development and transposition in plants.

Biochemistry.

Cytology.

Life sciences.

edited by Fritz Eckstein, David M.J. Lilley.

David M J Lilley

Fritz Eckstein

Electronic name

[Book]

Y