Volume I. Introduction / Maria-Regina Kula. Production and Isolation of Enzymes / Yoshihiko Hirose. Rational Design of Functional Proteins / Tadayuki Imanaka, Haruyuki Atomi. Enzyme Engineering by Directed Evolution / Oliver May, Christopher A Voigt, Frances H Arnold. Enzyme Bioinformatics / Kay Hofmann. Immobilization of Enzymes / James Lalonde, Alexey Margolin. Reaction Engineering for Enzyme-Catalyzed Biotransformations / Manfred Biselli, Udo Kragl, Christian Wandrey. Enzymic Conversions in Organic and Other Low-Water Media / Peter Halling. Enzymatic Kinetic Resolution / Jonathan M J Williams, Rebecca J Parker, Claudia Neri. Enzymes from Extreme Thermophilic and Hyperthermophilic Archaea and Bacteria / Costanzo Bertoldo, Garabed Antranikian. Volume II. Hydrolysis and Formation of Carboxylid Acid Esters / Hans Joachim Gais, Fritz Theil. Hydrolysis of Epoxides / Kurt Faber, Romano V A Orru. Hydrolysis and Formation of Glycosidic Bonds / Chi-Huey Wong. Natural Polysaccharide-Degrading Enzymes / Constanzo Bertoldo, Garabed Antranikian. Addition of Water to C=C Bonds / Marcel Wubbolts. Hydrolysis of Nitriles / Birgit Schulze. Formation and Hydrolysis of Amides / Birgit Schulze, Erik De Vroom. Hydrolysis of -Acylamino Acids / Andreas S Bommarius. Hydrolysis and Formation of Hydantoins / Markus Pietzsch, Christoph Syldatk. Hydrolysis and Formation of Peptides / Hans-Dieter Jakubke. Addition of Amines to C = C Bonds / Marcel Wubbolts. Transaminations / J David Rozzell, Andreas S Bommarius. Formation and Cleavage of P-O Bonds / George M Whitesides. Formation of C?C Bonds: Sections 14.1. 14.6 / Chi-Huey Wong. Formation of C?C Bonds: Enzymatic Synthesis of Cyanohydrins / Martin H Fechter, Herfried Griengl. Volume III. Reduction of Ketones / Kaoru Nakamura, Tomoko Matsuda. Reduction of Various Functionalities / Kaoru Nakamura, Tomoko Matsudo. Reduction of C=N bonds / Andreas S Bommarius. Oxygenation of C?H and C?C Bonds / Sabine Flitsch, Gideon Grogan, D Ashcroft. Oxidation of Alcohols / Andreas Schmid, Frank Hollmann, Bruno Buhler. Oxidation of Phenols / Andreas Schmid, Frank Hollmann, Bruno Buhler. Oxidation of Aldehydes / Andreas Schmid, Frank Hollmann, Bruno Buhler. Baeyer-Villiger Oxidations / Sabine Flitsch, Gideon Grogan. Oxidation of Acids / Andreas Schmid, Frank Hollmann, Bruno Buhler. Oxidation of C?N Bonds / Andreas Schmid, Frank Hollmann, Bruno Buhler. Oxidation at Sulfur / Karl-Heinz van Pee. Halogenation / Karl-Heinz van Pee. Isomerazation / Nobuyoshi Esaki, T Kurihara, K Soda. Introduction and Removal of Protecting Groups / Dieter Kadereit, Reinhard Reents, Duraiswamy A Jeyaraj, Herbert Waldmann. Replacing Chemical Steps by Biotransformations: Industrial Application and Processes Using Biocatalysis / Andreas Liese. Tabular Survey of Commercially Available Enzymes / Peter Rasor.