The Closed-Circuit Anaesthesia System.- Principles of Low Gas Flow Measurement for Closed-Circuit Systems.- The Biological Importance of Adequate Oxygen Supply: On-line Measurement of Oxygen and Carbon Dioxide.- Principles of Measurement of Anaesthetic Agent Concentrations in Closed-Circuit Systems.- The Present Status of Nitrous Oxide in Clinical Anaesthesia.- Measurements of Volatile Gases.- The Absolutely Tight Circuit System and the Problem of Excess Humidity.- Automatic Ventilation in Minimal Flow Anaesthesia.- A Closed Circuit.- Automatic Ventilation During Closed-Circuit Anaesthesia.- Discussion I.- Structure and Effectiveness of the Drager Microbe Filter 644 St.- Discussion II.- Comments on the Environmental Relevance of Commonly Used Inhalation Anaesthetics.- Discussion III.- Two Applications of a Differential Pressure Valve in Anaesthesia.- Measurement and Control of Air Pollution by Anaesthetic Gases and Vapours.- Measurement of Pulmonary Capillary Perfusion in Intubated Patients with a Non-invasive N2O-Rebreathing Method.- Discussion IV.- A Standardized Anaesthesia Machine.- Ergonomics and Anaesthesia: Autitory Alarm Signals in the Operating Room.- Rapid Setting of Intravenous Infusion Rates.- Presentation of an Ergnomically Designed Work Place for Anaesthesia.- Discussion V.- A Newly Designed Unit for the Recording of ECG, Temperature, Pulse Plethysmography, and Other Body-Surface Parameters.- Discussion VI.- The Organization of the Secretariat.- Discussion VII.- The Induction and Recovery Period of Inhalation Anaesthesia: A Considerable Improvement with Isoflurane.- Isoflurane.- Discussion VIII.- Quantitative Studies of Oxygen Exchange in Blood Substitution by Polymeric Stroma-free Haemoglobulin Solution.- Experiments with Haemoglobin Solutions as Perfusion and Infusion Solution.- The Technical and Physiological Aspects of Surgery and Anaesthesia Without Homologous Blood.- The Ability of Perfluorochemicals to Provide Microcirculatory Oxygenation.- Discussion IX.- Analytical Aspects of Some Anaesthesiologically Important Peptide Hormones.- Discussion X.- ?-Endorphin for Treatment of Pain.- Discussion XI.- Involvement of Pituitary Endorphins in Pain Perception and Their Importance in Pituitary-Stimulation-Induced Analgesia in Animals and Man.- Sufentanil: A Synthetic Narcotic for Total Intravenous Anaesthesia?.- Discussion XII.- On a New Topical Anaesthesia for Intra-uterine Manipulations.- Discussion XIII.- Frontal EEG/EMG Analysis: A Method of Assessing Depth of Anaesthesia. First Experience with an "Anaesthesia and Brain Activity Monitor".- Pneumatic Controlled Circulation.- Discussion XIV.- Heart-Cycle-Synchronized Jet Ventilation.- High-Frequency Ventilation for Laser Surgery of the Larynx.- Discussion XV.- The Pre-, Intra- and Postoperative Organization of Anaesthesia.- Development and Practical Use of a Computerized Anaesthesia Protocol.- Discussion XVI.- On-Line Graphic Presentation of Lung Mechanics During Mechanical Ventilation.- Check-List for the Drager Narkosespiromat 650.- Closing Statement.