Based on papers delivered at a meeting of the Fifth Congress of the International Society for Biomedical Research on Alcoholism, held June 16-17, 1990.
CONTENTS NOTE
Text of Note
Novel Pharmacological Interventions for Alcoholism; Copyright; Acknowledgments; Contents; Contributors; Part I General Methodologic Issues; 1 Animal Models for Testing Drug Effects on Alcohol Consumption; 2 Animal Models for Screening Drugs to Decrease Alcohol Consumption; 3 Medications for Alcohol Abuse and Dependence: Methodology for Clinical Studies; 4 Some Issues in the Evaluation of a Pharmacotherapy of Alcoholism; Part II Serotonin and Alcohol Consumption; 5 Serotonin and Alcohol Consumption; 6 Serotonergic and Dopaminergic Involvement in Ethanol Intake 7 Serotonin and Alcohol Consumption8 Basic and Clinical Studies on Serotonin, Alcohol, and Alcoholism; 9 Evaluation of the Effects of Serotonin Uptake Inhibitors in Alcoholics: A Review; Part III Opioids and Alcohol Consumption; 10 Opioids Modulate Rats' Propensities to Take Alcoholic Beverages; 11 The Enkephalinergic System and Maintenance of Ethanol Drinking; 12 The Relationship of Alcohol Drinking and Endogenous Opioids: The Opioid Compensation Hypothesis; 13 Naltrexone in the Treatment of Alcohol Dependence: Preliminary Findings Part IV The Role of Other Neurotransmitters in Regulating Alcohol Intake14 Neurotransmitter Systems Regulating Alcohol Intake; 15 Agents Which Modify Channels as Potential Treatments in Alcohol Withdrawal; 16 Management of Alcohol Consumption with Angiotensin Converting Enzyme Inhibitors: A Review of the Animal Findings; 17 Enalapril Does not Decrease Alcohol Intake in Normotensive Alcoholics; Poster Papers: General Methodologic Issues; Rational vs. reflexive alcohol drinking; RATS' INTAKES OF DIFFERENT ALCOHOLIC BEVERAGES DRUG-INDUCED SPECIFIC AND NONSPECIFIC CHANGES IN VOLUNTARY ETHANOL INTAKE BY RATSRationale for Alcoholism Treatment Based on Inhibition of Aldehyde Dehydrogenase; THE EFFECT OF LOW ALCOHOL BEVERAGES ON ALCOHOLISM LEVELS IN CANADA IN 1986; ALCOHOLISM, ANTISOCIAL BEHAVIOR, AND FAMILY HISTORY: A SYNOPSIS; PERCEPTION OF WHETHER DRUG OR PLACEBO HAS BEEN ADMINISTERED IS A DETERMINANT OF DRINKING REDUCTION; DISULFIRAM TREATMENT OF ALCOHOLISM; CONTROLLED RELEASE DISULFIRAM (DS) IMPLANT.; DEPOT DISULFIRAM: PHARMACOKINETICS AND CLINICAL EFFECTS DURING 28 DAYS FOLLOWING A SINGLE SUBCUTANEOUS DOSE MILDLY INTOXICATING LEVELS OF ALCOHOL PRODUCFS DIRECT MYOCARDIAL DEPRFSSION ON LEFT VENTRICULAR PERFORMANCEA HUMAN MODEL FOR TESTING DRUG-INDUCED CONCOMITANT VARIATIONS IN ALCOHOL CONSUMPTION AND DESIRE TO DRINK*; Poster Papers: Serotonin and Alcohol Consumption; MIANSERIN, A SEROTONERGIC ANTAGONIST, AND INTAKE OF AN ALCOHOLIC BEVERAGE; EFFECTS OF THE 5-HT UPTAKE INHIBITOR, SERTRALINE, ON ETHANOL, WATER AND FOOD CONSUMPTION; FLUVOXAMINE IS POORLY TOLERATED BY ALCOHOLICS; Poster Papers: Opioids and Alcohol Consumption; EFFECTS OF DIFFERENTIAL HANDLING ON RATS' INTAKE OF ALCOHOL
SUMMARY OR ABSTRACT
Text of Note
Novel Pharmacological Interventions for Alcoholism identifies priorities for focusing alcoholism and addiction research efforts during the coming years. A number of important issues concerning methodology, mechanisms, clinical evaluation, and pharmaceutical aspects are discussed.
TOPICAL NAME USED AS SUBJECT
Alcoholism -- Animal models -- Congresses.
Alcoholism -- Chemotherapy -- Congresses.
Alcoholism -- Research -- Methodology -- Congresses.