Introduction / Carl C. Correll and Phoebe A. Rice -- Role of water and effects of small ions in site-specific protein-DNA interactions / Linda Jen-Jacobson and Lewis A. Jacobson -- Structural basis for sequence-specific DNA recognition by transcription factors and their complexes / Manqing Hong and Ronen Marmorstein -- Indirect readout of DNA sequence by proteins / Catherine L. Lawson and Helen M. Berman -- Single-stranded nucleic acid (SSNA)-binding proteins / Martin P. Horvath -- DNA junctions and their interaction with resolving enzymes / David M.J. Lilley -- RNA-protein interactions in ribonucleoprotein particles and ribonucleases / Hong Li -- Bending and compaction of DNA by proteins / Reid C. Johnson, Stefano Stella and John K. Heiss -- Mode of action of proteins with RNA chaperone activity / Sabine Stampfl ... [et al.] -- Structure and function of DNA topoisomerases / Ken C. Dong and James M. Berger -- DNA transposases / Fred Dyda and Alison Burgess Hickman -- Site-specific recombinases / Gregory D. Van Duyne -- DNA nucleases / Nancy C. Horton -- RNA-modifying enzymes / Adrian R. Ferré-D'amaré