molecular fundmentals, methods and applications in modern biotechnology /
First Statement of Responsibility
edited by Michael Wink ; translated by Renate Fitzroy ... [et al.]
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Weinheim :
Name of Publisher, Distributor, etc.
Wiley-VCH,
Date of Publication, Distribution, etc.
c2006
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
lvi, 768 p. :
Other Physical Details
col. ill. ;
Dimensions
24 cm
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index
CONTENTS NOTE
Text of Note
Pt. I. Fundamentals of cellular and molecular biology -- The cell as the basic unit of life -- Structure and function of cellular macromolecules -- Structure and function of a cell -- Biosynthesis and function of macromolecules (DNA, RNA, and proteins) -- Distributing proteins in the cell (protein sorting) -- Diversity of organisms -- Pt. II. Standard methods in molecular biotechnology -- Isolation and purification of proteins -- Peptide and protein analysis with electrospray tandem mass spectrometry -- Isolation of DNA and RNA -- Chromatography and electrophoresis of nucleic acids -- Hybridization of nucleic acids -- The use of enzymes in the modification of nucleic acids -- Polymerase chain reaction -- DNA sequencing -- Cloning procedures -- Expression of recombinant proteins -- The patch clamp method -- Cell cycle analysis -- Techniques in microscopy -- Laser applications -- Pt. III. Key topics -- Genomics -- Functional genomics -- Protein-protein and protein-DNA interaction -- Bioinformatics -- Drug research -- Drug targeting and prodrugs -- Molecular diagnostics in medicine -- Recombinant antibodies and phage display -- Genetically modified mice (transgenic and knockout) and their impact on medicine -- Gene therapy : Strategies and vectors -- Modified DNA, PNA, and applications in medicine and biotechnology -- Plant biotechnology -- Biocatalysis in the chemical industry -- Pt. IV. Biotechnology in industry -- Industrial application (biotech industry, markets and opportunities) -- Patents in the pharmaceutical biotechnology industry : Legal and ethical issues -- Drug approval in the European union and the United States -- The emergence of a biotechnology industry -- The 101 of founding a biotech company -- Marketing