Contributors; Introduction; 1 The Metastatic Process: An Overview; 2 Physiopathology of Colorectal Metastasis; 3 The Genetics of Colorectal Cancer; 4 Epigenetics of Colorectal Cancer; 5 Cancer-Initiating Cells in Colorectal Cancer; 6 Epithelial-Mesenchymal Transition in Colorectal Cancer; 7 Cell Adhesion Molecules in Colon Cancer Metastasis; 8 Epithelial Cell Signalling in Colorectal Cancer Metastasis; 9 Angiogenesis and Lymphangiogenesis in Colon Cancer Metastasis; 10 Role of the Host Inflammatory Response in Colon Carcinoma Initiation, Progression and Liver Metastasis
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SUMMARY OR ABSTRACT
Text of Note
Colorectal cancer is the third most common cancer worldwide, and in many parts of the western world, it is the second leading cause of cancer-related deaths. This book covers colon cancer metastasis from the most fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, cell adhesion, natures of liver metastasis, angiogenesis and lymphangiogenesis, inflammatory response, prognostic markers, sentinel node and staging, and finally diagnosis and treatme