عنوان

Nuclear receptors in drug metabolism /

(Number (ISBN

0470086793 (cloth)

(Number (ISBN

9780470086797 (cloth)

Number

dltt

Title Proper

Nuclear receptors in drug metabolism /

General Material Designation

[Book]

First Statement of Responsibility

edited by Wen Xie

Place of Publication, Distribution, etc.

Hoboken, NJ :

Name of Publisher, Distributor, etc.

John Wiley & Sons,

Date of Publication, Distribution, etc.

c2009

Specific Material Designation and Extent of Item

xxii, 330 p., [8] p. of plates :

Other Physical Details

ill. (some col.) ;

Dimensions

25 cm

Text of Note

Includes bibliographical references and index

Text of Note

Drug metabolism : significance and challenges -- Establishing orphan nuclear receptors PXR and CAR as xenobiotic receptors -- Nuclear receptor-mediated regulation of phase II conjugating enzymes -- Nuclear receptor-mediated regulation of drug transporters -- Structure and function of PXR and CAR -- Xenobiotic receptor cofactors and coregulators -- Animal models of xenobiotic nuclear receptors and their utility in drug development -- Nuclear receptors and drug-drug interactions of prescription drugs and herbal medicines -- Genetic variants of xenobiotic receptors and their implications in drug metabolism and pharmacogenetics -- Beyond PXR and CAR, regulation of xenobiotic metabolism by other nuclear receptors -- Emerging role of retinoid-related orphan receptor (ROR) and its cross talk with LXR (liver X receptor) in the regulation of drug-metabolizing enzymes

0

Drugs-- Metabolism

Genetic regulation

Nuclear receptors (Biochemistry)

Drug Delivery Systems-- methods

Pharmaceutical Preparations-- metabolism

Receptors, Cytoplasmic and Nuclear-- metabolism

Receptors, Steroid-- metabolism

Number

Edition

Class number

Class number

Book number

Book number

Class number

Book Number

Xie, Wen,1967-

Date of Transaction

20160427144610.0

Electronic name

[Book]

Y