This completely revised second edition provides the state of the art perspective of the theory, practice and application of modern non-invasive imaging methods employed in exploring the structural and functional architecture of the normal and diseased human brain. It is organized in two major sections. The first describes advances in the understanding of human brain function in the areas of sensation, cognition and action. The second section describes major changes in thinking about how to image the brain brought about by the introduction of functional MRI. The unique single-laboratory nature of this volulme reflects the multi-disciplinary, integrated approach to modern imaging neuroscience