عنوان

Enzymes in synthetic organic chemistry /

(Number (ISBN

0080359418

(Number (ISBN

0080359426

(Number (ISBN

9780080359410

(Number (ISBN

9780080359427

Number

dltt

Title Proper

Enzymes in synthetic organic chemistry /

General Material Designation

[Book]

First Statement of Responsibility

C.H. Wong and G.M. Whitesides

Edition Statement

First edition

Specific Material Designation and Extent of Item

xvii, 370 pages :

Other Physical Details

illustrations ;

Dimensions

26 cm

Series Title

Tetrahedron organic chemistry series ;

Volume Designation

v. 12

Text of Note

Includes bibliographical references and index

Text of Note

4. Addition and Elimination of the Carboxyl Group. 5. Nucleoside Triphosphate Requiring Enzymatic Reactions. 6. Preparation of Derivatives of ATP Chiral at the [alpha]-, [beta]- or [gamma]-Phosphorus. 7. Phosphorothioate-Containing DNA and RNA (DNA-S and RNA-S). 8. DNA and RNA Oligomers. 9. Incorporation of Modified or Unnatural Bases into DNA or RNA. 10. Dehalogenation. 11. Synthesis of Chiral Methyl Groups. 12. S-Adenosylmethionine and Transmethylation. 13. Sulfate Activation and Transfer Reactions

Text of Note

4. Oxidoreductases that are Metalloenzymes -- Ch. 4. C-C Bond Formation. 1. Aldol Condensation. 2. Ketol and Aldol Transfer Reactions. 3. Addition of HCN to Aldehydes. 4. Acyloin Condensation. 5. C-C Bond Forming Reactions Involving AcetylCoA. 6. Isoprenoid and Steroid Synthesis. 7. [beta]-Replacement of Chloroalanine. 8. C-C Bond Formation Catalyzed by Vitamin B[subscript 12] -- Ch. 5. Synthesis of Glycoside Bonds. 1. Background. 2. Glycosyltransferases of the Leloir Pathway. 3. Non-Leloir Glycosyltransferases: Transfer of Glycosyl Donors from Glycosyl Phosphates and Glycosides. 4. Glycosidases. 5. Transglycosidases. 6. Synthesis of N-Glycosides. 7. Biological Applications of Synthetic Glycoconjugates. 8. Future Opportunities -- Ch. 6. Addition, Elimination and other Group Transfer Reactions (Phosphoryl-, Methyl-, Sulfo- and Amino-Transfer Reactions). 1. Addition of Water to Alkenes: Fumarase. 2. Addition of Ammonia to Double Bonds: Ammonia Lyases. 3. Transamination: Aminotransferases

Text of Note

Ch. 1. General Aspects. 1. Rate Acceleration in Enzyme-Catalyzed Reactions. 2. Michaelis-Menten Kinetics. 3. Enzyme Inhibition. 4. Specificity. 5. Improvement or Alteration of Enzyme Specificity. 6. Enzyme Stabilization and Reactor Configuration. 7. Cofactor Regeneration. 8. Enzyme Catalysis in Organic Solvents. 9. Multienzyme Systems and Metabolic Engineering. 10. Rational Design of New Enzymatic Catalysts -- Ch. 2. Use of Hydrolytic Enzymes: Amidases, Proteases, Esterases, Lipases, Nitrilases, Phosphatases, Epoxide Hydrolases. 1. Amidases. 2. Protease-Catalyzed Peptide Synthesis. 3. Proteases that Act as Esterases. 4. Acetylcholine Esterase. 5. Pig Liver Esterase. 6. Phospholipases. 7. Cholesterol Esterase. 8. Lipases. 9. Nitrile Hydrolysis Enzymes. 10. Epoxide Hydrolase. 11. Phosphatase -- Ch. 3. Oxidoreductions. 1. Nicotinamide Cofactor Dependent Oxidoreductions. 2. Dehydrogenases which Utilize Ketoacids as Substrates. 3. Other NAD(P)-Dependent Dehydrogenases

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Title

Enzymes in synthetic organic chemistry.

Enzymes

Organic compounds-- Synthesis

Number

Edition

Class number

Book number

Wong, Chi-Huey

Whitesides, G. M

Date of Transaction

20160712055852.0

Electronic name

[Book]

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