edited by Sue Shackleton, Department of Biochemistry, University of Leicester, Leicester, UK, Philippe Collas, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway, Eric C. Schirmer, Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, UK.
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
New York :
Name of Publisher, Distributor, etc.
Humana Press,
Date of Publication, Distribution, etc.
[2016]
SERIES
Series Title
Methods in molecular biology,
Series Title
Springer protocols
Volume Designation
1411
ISSN of Series
1064-3745 ;
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index.
SUMMARY OR ABSTRACT
Text of Note
"This book covers recent developments in the covariant formulation of quantum gravity. Developed in the 1960s by Feynman and DeWitt, by the 1980s this approach seemed to lead nowhere due to perturbative non-renormalizability. The possibility of non-perturbative renormalizability or "asymptotic safety", originally suggested by Weinberg but largely ignored for two decades, was revived towards the end of the century by technical progress in the field of the renormalization group. It is now a very active field of research, providing an alternative to other approaches to quantum gravity. Written by one of the early contributors to this subject, this book provides a gentle introduction to the relevant ideas and calculational techniques. Several explicit calculations gradually bring the reader close to the current frontier of research. The main difficulties and present lines of development are also outlined"--
Text of Note
This volume provides a wide range of protocols used in studying the nuclear envelope, with special attention to the experimental adjustments that may be required to successfully investigate this complex organelle in cells from various organisms. The Nuclear Envelope: Methods and Protocols is divided into five sections: Part I - Nuclear Envelope Isolation; Part II - Nuclear Envelope Protein Interactions, Localization, and Dynamics; Part III - Nuclear Envelope Interactions with the Cytoskeleton; Part IV - Nuclear Envelope-Chromatin Interactions; and Part V - Nucleo-Cytoplasmic Transport. Many of the modifications discussed in this book have only been circulated within laboratories that have conducted research in this field for many years. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and thorough, The Nuclear Envelope: Methods and Protocols is a timely resource for researchers who have joined this dynamic and rapidly growing field.