developed from a symposium sponsored by the Division of Organic Chemistry at the 188th Meeting of the American Chemical Society, Philadelphia, Pennsylvania, August 26-31, 1984 /
First Statement of Responsibility
Ronald G. Harvey, editor
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
ix, 406 pages :
Other Physical Details
illustrations ;
Dimensions
24 cm
SERIES
Series Title
ACS symposium series,
Volume Designation
283
ISSN of Series
0097-6156 ;
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and indexes
CONTENTS NOTE
Text of Note
Polycyclic aromatic hydrocarbon carcinogenesis : an introduction / Anthony Dipple -- Stereoselective metabolism and activations of polycyclic aromatic hydrocarbons / Shen K. Yang, Mohammad Mushtaq, and Pei-Lu Chiu -- Synthesis of the dihydrodiol and diol epoxide metabolites of carcinogenic polycyclic hydrocarbons / Ronald G. Harvey -- The Bay Region theory of polycyclic aromatic hydrocarbon carcinogenesis / Roland E. Lehr, Subodh Kumar, Wayne Levin, Alexander W. Wood, Richard L. Chang, Allan H. Conney, Haruhiko Yagi, Jane M. Sayer, and Donald M. Jerina -- Effects of methyl and fluorine substitution on the metabolic activation and tumorigenicity of polycyclic aromatic hydrocarbons / Stephen S. Hecht, Shantu Amin, Assieh A. Melikian, Edmond J. Lavoie, and Dietrich Hoffmann -- Mechanisms of interaction of polycyclic aromatic diol epoxides with DNA and structures of the adducts / Nicholas E. Geacintov -- X-ray analyses of polycyclic hydrocarbon metabolite structures / Jenny P. Glusker -- Polycyclic aromatic hydrocarbon-DNA adducts : formation, detection, and characterization / Alan M. Jeffrey -- The intercalation of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene metabolites and metabolite model compounds into DNA / P.R. Lebreton -- A mechanism for the stereoselectivity and binding of benzo[a]pyrene diol epoxides to DNA / Kenneth J. Miller, Eric R. Taylor, and Josef Dommen -- One-electron oxidation in aromatic hydrocarbon carcinogenesis / Ercole L. Cavalieri and Eleanor G. Rogan -- Hydroperoxide-dependent oxygenation of polycyclic aromatic hydrocarbons and their metabolites / Lawrence J. Marnett -- The mutational consequences of DNA damage induced by benzo[a]pyrene / Eric Eisenstadt -- Chemical properties of ultimate carcinogenic metabolites of arylamines and arylamides / Fred F. Kadlubar and Frederick A. Beland -- The in vitro metabolic activation of nitro polycyclic aromatic hydrocarbons / Frederick A. Beland, Robert H. Heflich, Paul C. Howard, and Peter P. Fu